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1、Healthtech in the MENA regionApril 2023Update forHealthtech in the MENA regionMay 2023Created by Dealroom.co for23-24 May 2023,Dubai World Trade CentrePage/2 Global startup&venture capital intelligence platformDealroom.co is a global data and intelligence platform for discovering the worlds most pro

2、mising startups and startup ecosystems.Founded in Amsterdam in 2013,we work with many of the worlds most prominent investors,entrepreneurs,and government organizations to provide transparency,analysis,and insights on venture capital activity.Our mission is to accelerate entrepreneurship and innovati

3、on through data and predictive intelligence for VCs,corporates,governments,and founders.Where the future of healthcare happens in the nowEMERGE 2050 I is a two-day networking event that connects healthtech innovations with investors at the Dubai World Trade Centre on 23-254 May 2023.HealthTech is a

4、booming sector for innovation and opportunity.Our program serves a dual purpose.It connects technology disruptors at startup and scale up stage with the capital and partnering needed to take projects to fruition.And,at the same time,it addresses the potential held by digital and telehealth in mitiga

5、ting the overwhelming costs of incumbent systems.Register today!23-24 May 2023,Dubai World Trade CentrePage/3 Omar J.Sati Managing Partner,DASH VenturesSophie SmithFounder and CEO,Nabta HealthEMERGE International Advisory Board Edward KliphuisPartner,Sofinnova PartnersAmal Ennan Managing Director No

6、rth Africa/Levant,Global VenturesMohammad ForsGlobal Head of Digital,AlmirallLee ShapiroManaging Partner,7wireVenturesFrancesca WuttkeChief Digital Officer,AlmirallMussaad Al RazoukiChief Investment&BDO,Kuwait Life Sciences CompanyLana Y.GhanemManaging Director,Hikma VenturesAlasdair ThongFounding P

7、artner,Selvedge VentureEMERGE Middle East Advisory Board Mohammad ForsGlobal Head of Digital,AlmirallAmal EnanManaging Director North Africa/Levant,Global VenturesOmar J.SatiManaging Partner,DASH VenturesSophie SmithFounder and CEO,Nabta HealthPage/4 EMERGE 2050 SpeakersAhmed Al-BaderCo-Founder&CEO,

8、SihaTObediah AytonDirector,Dhabi Hold CoMussaad Al RazoukiCIO,Kuwait Life SciencesViktoriya VasilenkoFounder&CEO,Knowledge Gate GroupAbhishek ShahFounder&CEO,Wellthy TherapeuticsIhsan JawadGeneral Partner,STVMohamed GamalGroup IT Director,UEMedicalPhilip-Moritz RussmeyerFounder&CEO,FITFILERoel Bulth

9、iusManaging Partner,INKEFEugene BorukhovichCOO;Founding Board Member,YourCoachAlexander HoffmannInvestment Director,M VenturesMarco MohwinckelIndependent Director and Chairman of the Board,AltibbiDoron DinsteinVenture Partner,Entre CapitalOliver Keown,MDDirector,Intuitive VenturesAbdulkader LamaaPar

10、tner,McKinsey Digital LabsEdward KliphuisPartner,Sofinnova PartnersCesare MagriFounder,4BetterDevices GmbHMark KrulFounder,Aglaia ManagementUnmesh LalGlobal Director Health,Frost&SullivanHakan EsinDirector,Diginova HealthDr.Sarper TanliManaging Director MEAMass General BrighamJeffrey A.StephensGener

11、al Partner,Infusion 51aAyoub GliaPostdoc Associate,CelltiroFaisal A.AlHusryPrincipal,Hikma VenturesSophie SmithFounder and CEO,Nabta HealthDr.Sadyk GusnievHealth Tech Expert&ResearcherClara RocheHealth Policy Insights,Economist ImpactPanos LiouliasFounder,Uni.FundDr Glen HagemannDirector,Mediclinic

12、Middle East34Mohammad ForsGlobal Head of Digital,AlmirallAmal EnanManaging Director North Africa/Levant,Global VenturesOmar J.SatiManaging Partner,DASH VenturesSophie SmithFounder and CEO,Nabta HealthPhilip-Moritz RussmeyerFounder&CEO,FITFILERoel BulthiusManaging Partner,INKEFEugene BorukhovichCOO;F

13、ounding Board Member,YourCoachAlexander HoffmannInvestment Director,M VenturesDr.Nadine H.-HaramCo-founder,ProximieIttai HarelManaging Partner,Pitango HealthtechEckhardt WeberManaging Partner,Heal CapitalMarco MohwinckelIndependent Director and Chairman of the Board,AltibbiDoron DinsteinVenture Part

14、ner,Entre CapitalOliver Keown,MDDirector,Intuitive VenturesAbdulkader LamaaPartner,McKinsey Digital LabsPrem TumkositMD,Merck Global Health Innovation FundSean SlovenskiChief Executive Officer,BioIQDudi KleinCo Founder&Managing Partner,Alive VC1.MENAs tech ecosystem 2.Global health tech3.Health tech

15、 in MENAPage/6 View all rounds Venture capital investment into MENA exploded in 2021 and 2022,launching the region into a higher echelon.Companies that raised big rounds include Getir,Astratech,Kitopi,and Dream Games.Source:dealroom.co|Created with Datawrapper.dePage/7 View all rounds Companies that

16、 raised big rounds in Q1 include Halan,One Moto,Floward,and Nana direct.Source:dealroom.co|Created with Datawrapper.deIn Q1 2023,VC investment activity has cooled down declining 70%YoY.Page/8 View all rounds Early stage startups that raised big rounds in Q1 include Remp People,Almentor,Tan,and Meshi

17、ni.Source:dealroom.co|Created with Datawrapper.deBut early-stage investment remains active.Page/9$1B+companies Companies that have at some point hit the$1B+valuation mark include Swvl,Careem,Hepsiburada,Getir.Istanbul TRKIYEDubai UAECairo EGYPTRiyadh SAUDI ARABIADubai UAERiyadh SAUDI ARABIACairo EGY

18、PTIstanbul TRKIYESource:dealroom.co So far,16 startups from the MENA region have passed the$1B+valuation mark.Page/10 Defining the Middle East&North AfricaNew Palo AltoTel AvivIsrael#1 country by VC funding per capita(2021)#6 country by number of unicorns (49 unicorns)$309B combined enterprise value

19、(up 3.5x since 2017)Gulf regionUAE is#1 MENA hub by total investment.Saudi Arabia is#3DubaiLagosNigeria#1 African country by VC funding5 unicorns created$17.5B combined enterprise value(up 8.3x since 2017)NairobiCape TownJohannesburgMENA region600M populationCairoIstanbulIsrael#1 country by VC fundi

20、ng per capita(2021)#6 country by number of unicorns(49 unicorns)$309B combined enterprise value(up 3.5x since 2017)Source:dealroom.co The MENA region has iself a 600M population,and has close links to Israel,Sub-Saharan Africa and key European hubs.Page/11 MENA used to be dwarfed by Israel but now t

21、he region has become more distributed.Source:dealroom.co|Created with Datawrapper.deMENA has grown its share to 37%of total investment into the Middle East and Africa,including Israel.Page/12 The Middle East and Africa have some of the fastest growing tech ecosystems globally.Growth in$venture capit

22、al invested from 2021 to 2022(red is decline,green is increase)Source:dealroom.co|Created with Datawrapper.dePage/13 Source:dealroom.co|Created with Datawrapper.deUAE,Trkiye and Saudi Arabia are the top three countries.Bahrain,Algeria and Tunisia were the fastest growing in 2022.Page/14 Dubai,Istanb

23、ul,Riyadh and Cairo are the top cities by venture capital.Riyadh is one of the fastest risers.Source:dealroom.co|Created with Datawrapper.deDubai,Istanbul,Riyadh and Cairo are the top cities by venture capital.34Mohammad ForsGlobal Head of Digital,AlmirallAmal EnanManaging Director North Africa/Leva

24、nt,Global VenturesOmar J.SatiManaging Partner,DASH VenturesSophie SmithFounder and CEO,Nabta HealthPhilip-Moritz RussmeyerFounder&CEO,FITFILERoel BulthiusManaging Partner,INKEFEugene BorukhovichCOO;Founding Board Member,YourCoachAlexander HoffmannInvestment Director,M VenturesDr.Nadine H.-HaramCo-fo

25、under,ProximieIttai HarelManaging Partner,Pitango HealthtechEckhardt WeberManaging Partner,Heal CapitalMarco MohwinckelIndependent Director and Chairman of the Board,AltibbiDoron DinsteinVenture Partner,Entre CapitalOliver Keown,MDDirector,Intuitive VenturesAbdulkader LamaaPartner,McKinsey Digital L

26、absPrem TumkositMD,Merck Global Health Innovation FundSean SlovenskiChief Executive Officer,BioIQDudi KleinCo Founder&Managing Partner,Alive VC1.MENAs tech ecosystem 2.Global health tech3.Health tech in MENAPage/16 View all rounds Global healthtech investment has reached$42 billion in 2022.Companies

27、 that raised big rounds include:Getir,Astratech,Kitopi,and Dream Games.Source:dealroom.coGlobal healthtech investment has reached$42 billion in 2022.Page/17 View Guide Source:dealroom.co|Created with Datawrapper.deGlobal healthtech investment has reached$42 billion in 2022.Page/18 Page/18 AI-drug di

28、scovery and digital therapeutics are the fastest growing segments.Source:dealroom.co|Created with Datawrapper.dePage/19 Page/19 Digital therapeutics startups have combined$31 billion value,up 8x.Combined enterprise value of digital therapeutic startups view online Source:Dealroom.co.Sum of the valua

29、tions of startups founded after 1990.Using estimated valuations based on most recent VC rounds,public markets and publicly disclosed valuations as of Dec 7,2022.$10B$20B$30B$31B$4B$0-200M$200M-1.0B(Future unicorn)$1.0-10B(Unicorn)Most valuable digital therapeutic startups view online$30BMusculoskele

30、talValuation:$6.2BUnited StatesDiabetes-obesityValuation:$2.0BUnited StatesDiabetes-obesityValuation:$2.0BUnited StatesMusculoskeletalValuation:$2.0BUSA,PortugalChronic careValuation:$1.5BUnited StatesNeuroscienceValuation:$1.5BSwitzerlandChronic careValuation:$1.0BUnited StatesChronic careValuation

31、:$440-660MUnited StatesDiabetes-obesityValuation:$320-480MSwitzerland201720182019202020212022 YTDPage/20 Source:Dealroom.co.|Created with Datawrapper.de|Some companies develop digital therapeutics for more than one therapeutic area.We have mapped 11 separate Digital Therapeutics segments.Combined VC

32、 funding(2017-2022 YTD)in digital therapeutic startups by selected therapeutic areas view online$2.4BBehavioural and mental health$2.4BDiabetes and dietary$1.7BMusculoskeletal health$1.3BOncology$1.1BFemtech$1.0BDigestive health$0.9BCardiology$8MUrinary diseases$8MUrinary diseases$81MRespiratory con

33、ditions$16MErectile dysfunction$7MOphthalmology34Mohammad ForsGlobal Head of Digital,AlmirallAmal EnanManaging Director North Africa/Levant,Global VenturesOmar J.SatiManaging Partner,DASH VenturesSophie SmithFounder and CEO,Nabta HealthPhilip-Moritz RussmeyerFounder&CEO,FITFILERoel BulthiusManaging

34、Partner,INKEFEugene BorukhovichCOO;Founding Board Member,YourCoachAlexander HoffmannInvestment Director,M VenturesDr.Nadine H.-HaramCo-founder,ProximieIttai HarelManaging Partner,Pitango HealthtechEckhardt WeberManaging Partner,Heal CapitalMarco MohwinckelIndependent Director and Chairman of the Boa

35、rd,AltibbiDoron DinsteinVenture Partner,Entre CapitalOliver Keown,MDDirector,Intuitive VenturesAbdulkader LamaaPartner,McKinsey Digital LabsPrem TumkositMD,Merck Global Health Innovation FundSean SlovenskiChief Executive Officer,BioIQDudi KleinCo Founder&Managing Partner,Alive VCDigital therapeutics

36、(also known as DTx)deliver evidence-based intervention that replaces or complements a diseases treatment.DTx enable remote management,improve prevention and treatment of chronic diseases,making treatment delivery direct and personalised via software or complementary medical device.Companion software

37、 in the patient journey:DTx influences the patients behaviour without using a pill(medication-free treatment),but using a support system.Regulation:DTx are heavily regulated,need to go through clinical testing to demonstrate safety and efficacy.The necessity for clinical evidence helps to demonstrat

38、e the therapeutic efficacy done by the software,but also the possible reimbursement by insurers and prescription by professionals.For instance,in September 2020,Germany was the first European country to cover prescribed apps:e.g.Kalmeda(tinnitus),Velibra(anxiety).Digital therapeutics:direct and pers

39、onalised medical intervention“beyond the pill”Source:Physician Burnout&Depression Report 2023 by Medscape.Survey replied by 9,100 U.S-based physicians across 29 specialties.https:/health.dealroom.co/lists/20489 See full landscapePage/22 Physician burnout has been increasing dramatically in recent ye

40、ars.The burnout rates are dramatically increasing:53%in 2023,from 47%in 2021,and jumped 26%since 2018.Health care shortages are the main cause behind raising levels of stress.Physicians who specialized in emergency medicine,internal medicine and pediatrics were more prone to suffer from higher level

41、s of burnout compared to their colleagues.In terms of demographics,women are also most likely to report feeling of burnout than men(63%vs 46%).Physicians stated that bureaucratic tasks and admin burden are by far the main driver of burnout.Burnout also takes a toll on physicians personal lives and c

42、ontributes to increasing in depression.Of those physicians reporting depression,64%said job burnout was the primary reason.53%of physicians said they are burnout1 in 5physicians reported experiencing depression What contributes most to your burnout?Lack of control/autonomyToo many bureaucratic tasks

43、Lack of respect from coworkersInsufficient compensationToo many work hoursComputerization of practice(EHRs)Lack of respect from patientsGovernment regulationsStress from treating COVID-19 patientsOtherSource:Physician Burnout&Depression Report 2023 by Medscape.Survey replied by 9,100 U.S-based physi

44、cians across 29 specialties.34Mohammad ForsGlobal Head of Digital,AlmirallAmal EnanManaging Director North Africa/Levant,Global VenturesOmar J.SatiManaging Partner,DASH VenturesSophie SmithFounder and CEO,Nabta HealthPhilip-Moritz RussmeyerFounder&CEO,FITFILERoel BulthiusManaging Partner,INKEFEugene

45、 BorukhovichCOO;Founding Board Member,YourCoachAlexander HoffmannInvestment Director,M VenturesDr.Nadine H.-HaramCo-founder,ProximieIttai HarelManaging Partner,Pitango HealthtechEckhardt WeberManaging Partner,Heal CapitalMarco MohwinckelIndependent Director and Chairman of the Board,AltibbiDoron Din

46、steinVenture Partner,Entre CapitalOliver Keown,MDDirector,Intuitive VenturesAbdulkader LamaaPartner,McKinsey Digital LabsPrem TumkositMD,Merck Global Health Innovation FundSean SlovenskiChief Executive Officer,BioIQDudi KleinCo Founder&Managing Partner,Alive VCPhysicians have been adopting personal

47、coping mechanisms such as exercise,talking and enhanced resting times.Also hospitals and health systems have been increasingly adopting different strategies to tackle burnout among health staff.Digital health tools have emerged in the last years as one of the key strategies to mitigate the workload

48、of physicians and support their daily tasks in several ways.For this report,we identified over 350+startups across 8 segments supporting physician and hospitals.Physicians are lookingfor new ways to cope withclinical efficiency bottlenecks.Source:Physician Burnout&Depression Report 2023 by Medscape.

49、Survey replied by 9,100 U.S-based physicians across 29 specialties.View all rounds See full landscapePage/24 Boston and the Bay Area are the leading Healthtech x Biotech hubs.Source:dealroom.co|Created with Datawrapper.deBiotech and pharma have traditionally been an ecosystem completely separate fro

50、m Healthtech.But they are increasingly overlapping.Exciting things are happening at the intersection of Biopharma&Healthtech,resulting in better alignment between biopharma,providers,and payers,as well as faster development of new treatments.View the Healthtech Guide hereView Guide Boston and the Ba

51、y Area are the leading Healthtech x Biotech hubs.Page/25 Page/25 Top categories in Life Sciences.Source:dealroom.co on the basis of Cipher.ai data|Created by Datawrapper.dePage/26 Page/26 Source:dealroom.co on the basis of Cipher.ai data|Created by Datawrapper.deEmerging patent categories:immunogeni

52、cs,surgical robotics and molecular oncology.34Mohammad ForsGlobal Head of Digital,AlmirallAmal EnanManaging Director North Africa/Levant,Global VenturesOmar J.SatiManaging Partner,DASH VenturesSophie SmithFounder and CEO,Nabta HealthPhilip-Moritz RussmeyerFounder&CEO,FITFILERoel BulthiusManaging Par

53、tner,INKEFEugene BorukhovichCOO;Founding Board Member,YourCoachAlexander HoffmannInvestment Director,M VenturesDr.Nadine H.-HaramCo-founder,ProximieIttai HarelManaging Partner,Pitango HealthtechEckhardt WeberManaging Partner,Heal CapitalMarco MohwinckelIndependent Director and Chairman of the Board,

54、AltibbiDoron DinsteinVenture Partner,Entre CapitalOliver Keown,MDDirector,Intuitive VenturesAbdulkader LamaaPartner,McKinsey Digital LabsPrem TumkositMD,Merck Global Health Innovation FundSean SlovenskiChief Executive Officer,BioIQDudi KleinCo Founder&Managing Partner,Alive VC1.MENAs tech ecosystem

55、2.Global health tech3.Health tech in MENAPage/28 Most valuable healthtech companies in the MENA regionValuationCategory$176MTelemedicine$170MAesthetic treatments$70MAesthetic treatments$58MInsurance products$40MTelemedicine$18MHospital digital transformation$16MTelemedicine$1.5 B should be hereSurgi

56、cal equipment and roboticsClinical decision supportDigital care(incl.telemedicine)MENA has an emerging healthtech ecosystem.Home testsDigital health insuranceMental healthFemtechDigital therapeuticsLegna Medical TechnologiesHospital operationsRemote monitoringLegna Medical TechnologiesSource Dealroo

57、m.co.In this report,MENA region excludes Israel.View online Page/29 Combined enterprise value of healthtech companies view online by launch year 1995-1999 2000-2004 2005-2009 2010-2014 2015-2021Healthtech companies in the MENA region have reached a combined value of$1.7B,an 8x increase since 2017.So

58、urce:Dealroom.co.In this report,MENA region excludes Israel.Combined enterprise value is the sum of the valuations of startups founded after 1990.Using estimated valuations based on most recent VC rounds,public markets and publicly disclosed valuations as of April 2023.Most valuable healthtech compa

59、nies in the MENA regionValuationCategory$176MTelemedicine$170MAesthetic treatments$70MAesthetic treatments$58MInsurance products$40MTelemedicine$18MHospital digital transformation$16MTelemedicine$1.8B$211M$0.5B$1.0B$1.5 B should be here$1.5B$1.7B 2017201620182019202020212022April 2023Page/30 UAE is

60、the healthtech hub of MENA.Healthtech investment in MENA has reached$106M in 2022.View all rounds Health tech companies that raised big rounds include Vezeeta,Altibbi,MS Pharma,and New Bridge PharmaceuticalsSource:dealroom.coCreated with Datawrapper.dePage/31 Page/31 UAE is the healthtech hub of MEN

61、A.Source:dealroom.co|Created with Datawrapper.dePage/32 Page/32 Telemedicine and biotechnology are the segments receiving most investment.Total VC funding(2016-2021)Most valuable companiesDigital care(incl.telemedicine)Clinical decision support with AIPractice management softwareRemote monitoring&we

62、arablesHospital operationsHome testDigital health insuranceMental healthSurgical equipment&roboticsDigital therapeuticsLegna Medical TechnologiesSource:dealroom.co|Created with Datawrapper.dePage/33 Founders have plenty of opportunities to attract funding,both from local and foreign investors.SeedSe

63、ries ASeries B+Funds with dedicated healthtech focus in the regionSector agnostic funds in the regionForeign funds active in the region1)Maverick,Global,Yozma,MEVP,Terra2)Pontifax,Israel Biotech Fund,Aurum,Alon,BioLight3)RA Capital,OrbiMed,Casdin,Cormorant,ForesiteSource:Dealroom.co.Not exhaustive.F

64、unds selected based on recent number of investments in Healthtech and(future)unicorns.Benslie InternationalFunds with dedicated healthtech focus in the regionForeign funds activein the regionSector agnostic funds in the regionBenslie InternationalSeries B+SeedSeries APage/34 Why Healtech in MENAis a

65、ttractive.Source:Dealroom analysis of data from OECD,Eurostat,CMS,WHO.Out-of-pocket expenses as%of health expenditureMENAWorld30%40%EUUSA10%20%600 million people$200 billion healthcare marketFast-growing populationConsumers have more power than in US and EU:an opportunity for tech600Mpeople$200BHeal

66、thcaremarketFast-growingpopulationConsumers have more power(an opportunity for tech companies)Page/35 Connecting the best Healthtech ideas with the leading Dealroom subscribers get an exclusive 25%discount off EMERGE 2050 tickets.Get your tickets today23-24 May 2023,Dubai World Trade CentrePage/36 C

67、heck out more Health Tech research reports.View reportsPage/37 Venture capital methodology and definitions.Investment numbers refer to rounds such as Seed,Series A,B,C,.late stage,and growth equity rounds.Venture capital investment figures exclude debt or other non-equity funding,lending capital,gra

68、nts and ICOs.Buyouts,M&A,secondary rounds,and IPOs are treated as exits:excluded from funding data.Investment rounds are sourced from public disclosures including press releases,news,filings and verified user-submitted information.Venture Capital investing and Startup data is sourced from and crunch

69、ed by Dealroom.co.Patent data is crunched by Dealroom.co on the basis of Cipher.ai Data.Data visualisations are built by Dealroom.co using Datawrapper.de or other tool where specifically mentioned.Companies designed to grow fast.Generally,such companies are VC-investable businesses.Sometimes they ca

70、n become very big(e.g.$1B+valuation).This report focuses,unless specified,on companies in the information age,i.e.after 1990 HQed in the MENA region,excluding Israel.When startups are successful,they develop into scaleups(50 people),grownups(500 people)and result in big companies.A unicorn is define

71、d as a rapidly scaling company(and tech enabled)that has reached a$1 billion valuation,on the basis of a funding round(unrealised),acquisition or IPO(realised).TaxonomyStartups,scaleups,grownups and techThis report focuses on the Healthtech industry.The healthtech industry is defined in the Dealroom

72、 Taxonomy as digital health startups developing technology(databases,applications,mobiles,wearables)to improve the delivery,payment,and/or consumption of care,with the ability to increase the development and commercialisation of products.A precise definition can be found here.Sub topics such as digital therapeutics and telemedicine are represented by tags in the platform.This can be under one single industry/sub industry or across multiple of them.Venture capital investment23-24 May 2023,Dubai World Trade Centre