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1、Top Pharma Trends to Watch in 2024Whats Inside1 Introduction2 CHAPTER 1 How the Pharmaceutical Industry is Changing3 CHAPTER 2 Recent Legislation Shaping the Industry5 CHAPTER 3 Trends Dominating the Future of Pharma11 CONCLUSION How Can AlphaSense Help You Stay on Top of Pharma Industry Development

2、s?IntroductionSince the onset of the COVID-19 pandemic,the pharma industry has experienced rapid,radical change.From billion-dollar funding for research on widespread health adversities to manufacturing new technologies to address them,the virus has ramped up lucrative investment opportunities in ne

3、arly every industry sector.And theres no sign of market activity slowing anytime soon,as geopolitical factors and variants of COVID-19 continue to open new doors for funneling capital.But this financially prosperous time for pharma companies has C-Suite leadership and stakeholders wondering:what doe

4、s the future of healthcare entail?Deciphering future diseases and potential treatments is imperative to distinguish between a worthy investment or financing an industry fad.Thats why more and more pharma companies are leveraging market intelligence platforms to see what their competition,Wall Street

5、,and the industry is saying and to find the answers they need.Using the AlphaSense platform,we dug into the pharma trends likely to dominate 2024 and beyond.Below,learn how digital transformation,artificial intelligence(AI),the adoption of big data,and much more are redefining what medicine looks li

6、ke for both patients and providers.1CHAPTER 1How the Pharmaceutical Industry is ChangingWhen the pandemic began in 2020,the pharmaceutical industry faced a series of challenges.COVID-19 changed the conditions in which Americans were willing to go back or even continue working,with many reconsidering

7、 their career paths.In 2021,more than 47 million workers quit their jobs while 32%of Americans switched professions,ushering in a wave of unemployed workers and,consequently,the Great Resignation.This alone has pushed pharma companies to reconsider how they can fulfill demand without the use of huma

8、n workers.Additionally,the Russia-Ukraine war has extensively affected global supply chains.Essential commodities that many sectors rely on are no longer guaranteed,forcing suppliers to reconsider how they can acquire what they need to meet their end users demands.As the strain on materials continue

9、s to grow in this conflict,the monetary deficit brought on by this shortage has ushered in staggering inflation prices.According to a report by the Department of Health and Human Services,drug prices on more than 1,200 prescription drugs rose faster than inflation between July 2021 and July 2022,ris

10、ing on average 31.6%.These market-disrupting events have forced pharmaceutical companies to strategize how providers can continue to treat without a steady supply of materials or human talent.The results:medical processes streamlined with the use of machine learning,treatments administered and monit

11、ored in digital spaces,artificial intelligence playing an increasing role in our healthcare systems,and much more.2CHAPTER 2Recent Legislation Shaping the IndustryHealthcare systems globally are undergoing significant reforms,impacting drug manufacturers through stricter access and pricing regulatio

12、ns.Specifically within the U.S.,the government has initiated negotiations for the first 10 products under the Inflation Reduction Act(IRA).Through the IRA,Congress seeks to make prescription drugs more affordable with reforms that will reduce the price of drugs and limit out-of-pocket costs for many

13、 Medicare patients.In todays healthcare reality,prescription drugs account for about 20%of Medicare patients out-of-pocket costs.Spending on prescription drugs continues to grow as other health spending has decreased.But when the initial IRA negotiations took place last year,the pharma industry resp

14、onded by launching a series of new lawsuits that invoke the First and Fifth Amendments.Merck&Co.and Bristol Myers Squibb,for instance,are challenging the IRAs constitutionality.Meanwhile,lobbyists and their co-litigants are incorporating the Eighth Amendment into their lawsuit.According to a Pharma

15、Voice article,William Soliman,CEO and founder of the Accreditation Council for Medical Affairs,views this approach of litigation as strategic.“They are using a multi-pronged approach in tandem,”he says.“The purpose(is)to hit the government on all ends and to ultimately force them to overturn or seri

16、ously limit the impact the IRA can have.”3Meanwhile,proposed EU legislation aims to reduce the exclusivity window for new drugs from 10 to eight years if they do not launch in all 27 member states within two years.Germany is also considering reforms to its pharmaceutical regulations(AMNOG 2.0)to con

17、trol drug costs,while Italy is restructuring the Italian Medicines Agency(AIFA).In Japan and China,similar efforts are underway to lower drug prices.These reforms collectively signal a period of uncertainty and potential revenue pressure for the pharmaceutical industry.4CHAPTER 3Trends Dominating th

18、e Future of PharmaCOVID-19 renewed interest in modernizing healthcare,as an increasing amount of investor attention is being spent on scouting for future growth areas for pharma.Moreover,weaknesses that existed in medical systems before the pandemic have refreshed concern from companies,stakeholders

19、,and the like to devise solutions to overcome them.In addition to regulatory and national legislation(i.e.,The Inflation Reduction Act,which mandates Medicare to financially cover physician-administered biosimilars at an ASP plus 8%rate)to driving stakeholder engagement,competition couldnt be thicke

20、r to find the next big vaccine,management system,or therapy.VaccinesIn 2020,Pfizer,Moderna,and Johnson&Johnson competed to create the first effective COVID-19 vaccine.While all served the same purpose of immunizing recipients against the virus,conversations emerged about which vaccine outperformed t

21、he others.This inevitable need for consumers to compare and rank treatments has only pushed pharma companies to invest in crafting an industry-changing vaccine.And recent news shares promise of a future where some of the worlds leading causes of death(i.e.,cancer,HIV,etc.)are eradicated with a singl

22、e,or a series,of shots.5AlphaSense shows a 130%increase in aggregate documents mentioning“vaccines”over the last 12 monthsPfizer has stirred up vaccine excitement with their recent announcement to launch five“new vaccines,”plus two new medicines in oncology and immuno-inflammation.Meanwhile BioNTech

23、,which collaborated with Pfizer to create its COVID-19 vaccine,said immunization against cancer could be possible as soon as 2030.Experts agree that pharma companies whove had a leg in the COVID-19 vaccine race are set up for future vaccine-crafting success.Artificial IntelligenceMentions of AI appl

24、ications within healthcare are steadily rising within the AlphaSense platform,especially within our library of patent applications and clinical trials.Physicians,surgeons,and nurses are leveraging artificial intelligence to retrieve insightful analytics that drive care optimization and workflow effi

25、ciency through predictive,AI-powered systems.Likewise,pharma manufacturers are sharing how theyre integrating AI in telemedicine and imaging to treat various conditions,from diabetic retinopathy to blood cancer and even internal bleeding.And to aid providers,pharmaceutical manufacturers are incorpor

26、ating AI to assist medical professionals in their patient consultations(i.e.,AI voice-activated assistants to transcribe doctors notes).24,487TOTAL DOCUMENTS31 3.85%90D CHANGE26 OCT 2326 JAN 2426 APR 24Document Trend1k2k3k6In the eyes of medical manufacturers,there seem to be endless possibilities f

27、or how AI can be woven into healthcare.“Applying AI to big data in life sciences can help companies reshape business models,streamline biopharma manufacturing,and enhance everything from cognitive molecule research and clinical trial data flow to self-healing supply chain applications and product in

28、telligence,”Deloitte stated.“It can also enable life sciences companies to be more personalized and authentic in how they engage with health care professionals,patients,and other stakeholders.”Machine LearningMachine learning has widely expanded the capabilities of not only medical manufacturers but

29、 providers.The COVID-19 virus propelled the concept of replacing human workers with robotsmechanical workers that operate on“machine learning”or the application of AI that enables systems to learn and improve from experience without being explicitly programmed.Patents and clinical trials found withi

30、n the AlphaSense platform have been a steady,reliable source of information on how robotics are continuously revolutionizing the ways in which doctors diagnose and even prescribe.Machine learning in pharma focuses not on replacing a doctor but on enhancing their medical expertise using artificial in

31、telligence programs.By combining the knowledge that a physician has and the vast amount of data available to medical professionalsranging from new drugs to disease symptoms,drug interactions,and patient outcomesmachine learning can provide deeper insight into more precise patient diagnoses and,conse

32、quently,treatment.Already,doctors are using AI programs in x-ray readings and CT scans to identify suspicious nodules and lesions in lung cancer patients.7Big DataBased on equity research found within the AlphaSense platform,industry experts expect big data to have the greatest impact on the pharmac

33、eutical industry.In addition to AI,big data is providing pharmaceutical companies with predictive,prescriptive,and diagnostic analytics that have led to new drug discoveries and developments.Further,it allows scientists to work with and link large datasets,detect patterns in real-time,predict outcom

34、es,undertake dynamic risk scoring and test hypotheses.By applying these strategies to better inform decision-making,healthcare systems can leverage big data to improve the efficiency of research and clinical trials,building new tools for physicians,patients,and even regulators.Documentation in the p

35、latform reveals that,currently,multiple healthcare companies,ranging from multi-provider groups to single-physician offices,are adopting big data analytics to also maximize revenues,increase personalized patient care services,quickly yet effectively detect healthcare fraud,and review clinical trials

36、 and medical records.In addition,big data has helped reduce some of the astronomical costs and drawbacks associated with clinical trials.JAMA reports that the estimated research and development spent to develop a new drug ranges around$1.1 billion,including the costs of failed clinical trials.Thats

37、why recruiting qualified candidates for a clinical study is essential to maintaining a budget.Big data can eliminate the guesswork and time constraints to find the right participants by leveraging genetic makeup,disease status,patient data,demographics,past clinical trial data,and much more.8Gene Th

38、erapy2022 proved to be a major milestone for the global gene therapy space,as a slew of innovative treatments for chronic diseases were launched.In August of 2022,bluebird bios Zynteglo,a one-time treatment that addresses beta-thalassemia at the genetic level,was approved for use within the US by th

39、e FDAthe first approval by the administration for gene therapy in over three years.Internationally,the European Medicines Agency also approved a major gene therapy.PTC Therapeutics Upstaza will treat children and adults with severe aromatic L-amino acid decarboxylase(AADC)deficiency,an inherited dis

40、ease that affects the nervous system leading to symptoms that include weak muscle tone and lack of limb movement.Over the last six months,AlphaSense has tracked a 132%increase in mentions of“big data”within the pharmaceutical industryDrug development for disease management also brings a lens to a my

41、riad of pharma supply chain aspects.Investigating scalable and cost-effective production processes,balancing speed-to-market and product quality,as well as tackling delivery and dosage challenges will be the priorities for those getting investing in new gene therapies.20,724TOTAL DOCUMENTS21 8.45%90

42、D CHANGE26 OCT 2326 JAN 2426 APR 24Document Trend50010001500200025009Digital TherapeuticsIn the AlphaSense platform,conversations around digital therapeutics being viewed as an accessible healthcare option for global crisesa concern derived from the COVID-19 pandemicgrew in number.Evidence-based,cli

43、nically-approved,and FDA-cleared software that can be accessed through ones medical device and work in tandem with the prescriptions ones physician prescribes is filling a gap that one-on-one medical consultations could not.But,by having patients rely on software for medical guidance rather than in-

44、person medical consultations,many are digging deeper into the pathways in which the FDA legitimizes digital therapeutics.However,experts believe that if digital therapeutics pass through the traditional systems set in place by the administration,then patient and provider trust would likely follow.Ev

45、entually,digital therapeutics could become the norm.“With the FDA,as long as there are clinical trials that are completed and everything is run by people that have experience in the field,as long as theres enough research and enough science behind it,with the FDA,things should be passed accordingly.

46、Thats how we probably progress in the medical field and how we evolve in terms of ways to continue saving patient lives,”says an expert in one of our Expert Insights calls.10How Can AlphaSense Help You Stay on Top of Pharma Industry Developments?Pharma industry trends evolve on a near-constant basis

47、,making it a full-time endeavor to decipher which ones to pursue with your attention and capital.Thats why more C-Suite executives are implementing marketing intelligence platforms into their operations to accelerate their research with AI.AlphaSenses AI search engine and extensive content library,w

48、hich aggregates business documents from over 10,0000 content sources,allow our clients to remain at the forefront of their respective industries.11About AlphaSense The worlds most sophisticated companies rely on AlphaSense to remove uncertainty from decision-making.With market intelligence and searc

49、h built on proven AI,AlphaSense delivers insights that matter from content you can trust.Our universe of public and private content includes equity research,company filings,event transcripts,expert calls,news,trade journals,and clients own research content.Our platform is trusted by over 4,000 enterprise customers,including a majority of the S&P 500.Founded in 2011,AlphaSense is headquartered in New York City with over 1,300 people across the globe and offices in the U.S.,U.K.,Finland,India,and Singapore.Learn More at Alpha-S12