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1、Strategy&Rethinking ObesityFebruary 2025Rethinking ObesityCross-sector,consumer-centered strategies to embed lasting changeFebruary 2025Strategy&Rethinking ObesityFebruary 2025Obesity not only impacts the health and wellness of an individual but creates a significant global financial burden,projecte

2、d to reach$4.3 trillion by 2035The impact of obesitySources:Mayo Clinic,US Centers for Disease Control and Prevention,World Obesity Atlas 20232Projected prevalence of obesity in selected countries by 2035Obesity is a complex medical condition causing numerous health complications including(but not l

3、imited to)Heart diseaseType 2 diabetesCertain cancersWith the rate of obesity continuing to climb,it is expected that by 2035:1 in 4(nearly 2 billon)people will be living with obesity OsteoarthritisPsychological issues such as anxiety and depressionThe global financial burden due to overweight and o

4、besity is estimated to reach US$4.32 trillion58%41%46%47%46%36%18%8%Strategy&Rethinking ObesityFebruary 2025Consumers across the US and Europe are willing to spend US$400bn+to achieve their weight loss goals,but commit only to short-termSource:Strategy&projection based on a nationally representative

5、 study in the US,DE and the UK with over 2,000 respondents(Strategy&x Appinio Obesity Survey).Europe includes 49 countries(excl.Russia)Should I start a 12-week weight loss program?Do I need medical treatment?For how long?Should I sign up to the gym for the next year?What weight-loss solutions best f

6、it my current lifestyle and state of health?How can I stay focused and motivated on my weight loss journey?How should I evolve my behaviors to keep the weight off?How can we evolve from a fragmented,short-term approach to weight loss to a long-term,sustainable and personalized model of obesity care

7、and prevention?How does my weight management improve my overall health and prevent other diseases?Strategy&Rethinking ObesityFebruary 2025Any person looking to lose weight has an abundance of choice,but there is little personalization or integration into everyday lifestyleSelected weight loss option

8、s and examplesNestle,SlimfastNoom,BetterHelpBehavioral therapy and coachingPhysical activity and fitness coachingNutrition and dietary guidanceStructured weight loss programsMulti-omics approaches,and more Dietary foods and food supplementsMedicationsSurgical interventionsGastric sleeve,gastric bypa

9、ssWeight Watchers,OptaviaMyFitnessPal,YazioOrlistat,Semaglutide,Tirzepatideconsumers across the US,Germany,and the UK about their weight loss goals and experience2000+We asked Exemplary integrations between offeringsFitbit,Apple,Peleton4Strategy&Rethinking ObesityFebruary 2025While diet and exercise

10、 remain the most favored options,consumers believe that a multi-layered approach to weight management is the way forward Consumer beliefs and behaviors(1/2)Source:Strategy&x Appinio Obesity Survey,Katya Peri,Mark Eisenberg-Review on obesity management:diet,exercise and pharmacotherapy:BMJ Public Hea

11、lth 20243 and 4 Based on respondents who have tried at least one solution Consumers have predominately tried one or two solutions to lose weight3Consumers would allocate around half of their weight loss spending on diet and exercise5Half of consumers have tried only diet and/or exercise to lose weig

12、ht424%have tried a mix of other weight loss solutions(incl.OTC or Rx medication)with or without diet and exercise45%of spend is allocated across supplements,medication,surgery and other solutions30%34%17%19%Diet and/or exerciseHolistic weight loss programsDiet and/or exerciseHolistic weight loss pro

13、grams58%18%8%47%of consumers agree that sustainable long-term weight loss is only achievable with a holistic,multi-solution approach281%The scientific community recommends a multi-solution,tiered approach to obesity management(including lifestyle changes and pharmacotherapy)One solutionTwo solutions

14、Three solutionsFour or more solutions5Strategy&Rethinking ObesityFebruary 202518%are not willing to spend money on weight loss14%would generally never take a weight loss medication additionally,current weight loss behaviors suggest a short-term focus,though most consumers agree to the need for long-

15、term obesity managementConsumer beliefs and behaviors(2/2)Source:Strategy&x Appinio Obesity Survey;Weight loss options include diet plan,special diet foods,exercise,medication etc.8 Based on those who would spend on a weight loss solution 9 Only consumers with BMI=30(obese)considered,aligned with th

16、erapeutic indication for anti-obesity medicationsBut most consumers are willing to spend money(across all weight loss options)for the short-term only to achieve weight loss goals712%26%12 months25%31%30%44%If weight loss medications were covered by health insurance,most consumers would still only ta

17、ke them for the short-term912 monthsof consumers agree that obesity is a medical condition that requires continuous and long-term treatment686%6Average monthly spend8:$255161110Strategy&Rethinking ObesityFebruary 2025Obesity care must evolve to drive sustainable outcomes for consumers over the long-

18、term personalization and behavioral change are vitalUnlocking the future of obesity care and prevention71Reorient consumers short-term motivations toward longer-term changeEncourage long-term behavioral change and sustainable weight management to treat or prevent obesity,alongside helping consumers

19、to achieve their short-term weight loss goals2Drive holistic and personalized weight loss solutionsConsider individuals health profile,lifestyle and personal preferences to ensure a sustainable approach to obesity care and/or prevention over the long-termCreate shared ownership of obesity care and o

20、utcomesGenerate sustainable business and care models for providers and consumers by sharing both costs and benefits of long-term obesity management and prevention3Integrated data and AI solutions to capture multidimensional,diverse consumer data and enable personalizationEcosystem,cross-sector and p

21、ublic-private partnershipsto support closer cooperation and new business modelsEnablersStrategiesIf these elements are addressed effectively,obesity care will become one of the key building blocks of the LIFEcare system,which the Future of Healthis evolving towardsComprehensive educationon the compl

22、exity of obesity and risk of associated diseases,as well as on the need for sustainable weight management 231Strategy&Rethinking ObesityFebruary 2025Certain key strategies will be fundamental in converting disease treatment and prevention into a unified obesity managementStrategies deep dive why cho

23、ose the strategy and how to realize itSource:1)Strategy&x Appinio Obesity Survey;2)Hall K,Kahan S.Maintenance of lost weight and long-term management of obesity:NIH 2018;3)Rotunda W,Rains C,Jacobs SR,et al.Weight Loss in Short-Term Interventions for Physical Activity and Nutrition Among Adults With

24、Overweight or Obesity:A Systematic Review and Meta-Analysis:CDC 2024;4)Thorpe K,Toles A,Shah B,et al.Weight Loss-Associated Decreases in Medical Care Expenditures for Commercially Insured Patients With Chronic Conditions:JOEM 2021;5)Carrello J,Lung T,Baur LA,Hayes A.Economic benefits of reducing chi

25、ldhood and adolescent overweight and obesity in Australia:Public Health Res Pract.2024 Reorient consumers short-term motivations toward longer-term changeMove toward holistic and personalized weight loss solutionsCreate shared ownership of obesity care and outcomesWith 70%of consumers aiming to lose

26、 weight and preferring short-term programs,many will regain the weight.1,2,3)Optimal solutions will support long-term change for sustainable outcomesEncourage alignment across relevant industries to create a unified voice,shifting the perception of weight loss from a short-term activity to a longer-

27、term journeyDesign solutions which support positive behavioral change,through incremental steps,toward a longer-term approach to weight managementBody weight is affected by numerous factors,from genetics to social determinants such as income and access to healthcare.Solutions need to be personalized

28、 to consider this multitude of factorsIntegrate solutions which address the physical,mental and emotional aspects of health into a single offering for a truly personalized approach to obesity careUtilize diverse patient data to determine the most effective and sustainable weight loss options accordi

29、ng to a consumers profileAchieving sustainable weight management habits requires both intrinsic consumer motivation and external support.Moreover,lowering obesity rates and preventing related diseases4,5)can reduce healthcare costs and boost economic outputDevelop new financing models for consumers

30、to make weight loss solutions more affordableImplement a value-based care model for public/private services to drive greater ownership of consumer outcomes by healthcare providersExecution of these key strategies will look different across the world due to country-specific considerations such as hea

31、lth systems,data privacy,regulations and consumer behaviorsWhy it is importantInitiatives to realize it(non-exhaustive)8Strategies123Strategy&Rethinking ObesityFebruary 2025Now is the critical time to accelerate the change in obesity care proactive steps from all ecosystem players are requiredFuture

32、 stakeholder roles(non-exhaustive)1)Including GP,dietician,behavioral therapist,health coach etc.Across all roles:create cross-sector partnerships to integrate diverse data and enable holistic and personalized solutions for consumersHealthcare providers1)Overweight/obesity check at every visit Patie

33、nt education and data generation Multi-disciplinary collaboration and data sharingPharma and biotech Personalization of medical treatment New financing options for medical treatment Diagnostic solutions for early detection of health risks related to obesityGovernment and research National awareness

34、and communication initiatives to educate the pubic Policies and regulatory frameworks to enable new care and business modelsPharmacies and drug stores Education about obesity Consumer support at critical points of their journeyFood and beverages New,integrated,product offerings established for speci

35、fic consumer segments Digital services integrating product information,shopping habits and specific weight loss journey stage(Medical)Technology providers Gamification approaches to support weight loss Data exchange platforms(e.g.via tokenization)Devices for continuous measurement of biomarkersSport

36、/fitness providers Personalization of fitness offerings based on individual health profile,lifestyle and preferences Healthcare insurers Co-creation of innovative financing options Incentivization of sustained change in weight loss 9Strategy&Rethinking ObesityFebruary 2025Where to start?Industry pla

37、yers need to ensure clarity on their role in the ecosystem,introduce the right capabilities,and prepare to form partnershipsKey actions to take today Do the companys product and service offerings support the consumers long-term journey in obesity management?What unique capabilities can the company o

38、ffer to help secure the future of obesity care?Does the company see itself as a solution provider,platform provider and/or an ecosystem orchestrator in obesity care?What will this defined role mean for the companys future business model?Does the company have the right capabilities to build sustainab

39、le cross-sector partnerships?How does the company business model need to change to allow for partnerships at scale?Pressure-test offerings and capabilitiesDefine role in the ecosystemPrepare to partner at scale10Strategy&Rethinking ObesityFebruary 2025Contact us if you are interested to find out mor

40、eOverall studyLocal study insightsFuture of HealthIndustry contactsRahul KhatriManagerIryna ScheurlenDirectorJonas GrefeDirectorThomas SolbachPartnerManuel MeskePartner11UK Thalita MarinhoPartnerDE Iryna ScheurlenDirectorUS Gurpreet SinghPartnerHarald DutzlerPartnerRetail and Consumer goods Thomas S

41、olbachPartnerPharmaHealthcareThank 2025 PwC.All rights reserved.PwC refers to the PwC network and/or one or more of its member firms,each of which is a separate legal entity.Please see for further details.Disclaimer:This content is general information purposes only,and should not be used as a substi

42、tute for consultation with professional advisors.Strategy&Rethinking ObesityFebruary 2025Strategy&DateAppendixStrategy&13February 2025Rethinking ObesityStrategy&Rethinking ObesityFebruary 2025Survey results from nationally representative cohorts from the US,Germany and the UK were used to unearth in

43、sights into consumer behavior and beliefsAppendix A:Survey analysis methodology and assumptionsSource:Strategy&x Appinio Obesity Survey 14#ReferenceMethodology and assumptions1Consumers across the US and Europe are willing to spend US$400bn+to achieve their weight loss goalsQ:Which statement best de

44、scribes your weight management goals I have tried/not tried to lose weight within the last 12 months and/but looking to do so in the next 12 months and for how long would you be willing to spend(amount of money answered in previous question)per month to achieve your weight loss goals?Median values f

45、or each spend range option have been used for sizing calculations.The total population spend in the US,Germany and the UK has been calculated by extrapolating the spend of the surveyed cohort to the national population by age and income.Total spend for the rest of Europe(49 countries excl.Russia)was

46、 calculated by extrapolating results from German respondents based on PPP and population data.281%of consumers agree that sustainable long-term weight loss is only achievable with a holistic,multi-solution approachQ:To what extent do you agree with the following statements about a holistic approach

47、towards weight loss Sustainable long-term weight loss is only achievable with a holistic approach,and not with a single solution?“Agree completely,”“Agree”and“Somewhat agree”responses were counted as consumers agreeing with the statement.Based on all 2,150 responses3Consumers have predominately trie

48、d one or two solutions to lose weightQ:What have you tried in the past to lose weight?Based on 1964 responses(proportion of those who have tried at least one weight loss solution)4Half of consumers have tried only diet and/or exercise to lose weightQ:What have you tried in the past to lose weight?Di

49、et and/or exercise category includes“exercise”,“diet or general adjustment of eating behaviors”,“special weight loss or diet foods”,or a combination of these response options.Holistic weight loss programs category counted as the number of respondents who selected“holistic weight loss programs”regard

50、less of additional options chosen.Based on 1964 responses(proportion of those who have tried at least one weight loss solution)5Consumers would allocate around half of their weight loss spending on diet and exerciseQ:How much money are you willing to spend on achieving your weight loss goals per mon

51、th across all measures and how would you distribute your budget for weight loss measurements across your desired options?Proportion of spend was calculated using an assumed value for each spend range option,in USD.Based on 1,763 responses(proportion of those who would spend on a weight loss solution

52、)686%of consumers agree that obesity is a medical condition that requires continuous and long-term treatmentQ:To what extent do you agree with the following statements about a holistic approach towards weight loss Obesity is a medical condition,requiring continuous long-term treatment?“Agree complet

53、ely,”“Agree”and“Somewhat agree”responses were counted as consumers agreeing with the statement.Based on all 2,150 responses7But most consumers are willing to spend money(across all weight loss options)for the short-term only to achieve weight loss goalsQ:For how long would you be willing to spend(am

54、ount of money answered in previous question)per month to achieve your weight loss goals?Based on all 2,150 responses8Average monthly spend:US:$255,DE:161,UK:110Q:How much money are you willing to spend on achieving your weight loss goals per month across all measures?Average monthly spend was calcul

55、ated using an assumed value for each spend range option.Based on 1,763 responses(proportion of those who would spend on a weight loss solution)9If weight loss medications were covered by health insurance,most consumers would still only take them for the short-termQ:For how long would you take a weig

56、ht loss drug if it was paid for by your health insurance?Based on 640 responses(proportion of respondents with obesity(BMI=30)aligned with therapeutic indication for anti-obesity medications)Strategy&Rethinking ObesityFebruary 2025Responses across countries are largely similar;some observed differen

57、ces may indicate how local consumers behave and spend on solutionsAppendix B:Selected survey result breakdown by countrySource:Strategy&x Appinio Obesity Survey;WL=weight loss,LT=long-term15The desire to lose weight in the next 12 months is similar across the US,DE and the UK,with UK consumers the h

58、ighest at 73%1DE&UK consumers show similar willingness to spend on WL drug vs other solutions,US consumers less willing to spend on medication2USDEUKAverage spend among those who would spend on a weight loss solution$255161110Average spend among those who would spend on a weight loss medication$2191

59、69107Key factors for choosing weight loss medication seen similarly across countries,with importance of price&scientific evidence varying slightlyMore consumers would spend a shorter period of time on weight loss drugs compared to general solutions,especially in DE and UK43USDEUK%of consumers select

60、ing a factor as important for the choice of a WL medicationPrice48%41%46%LT sustainability(keeping weight off)41%37%40%Scientific evidence on weight loss27%36%34%USDEUK%of consumers wiling to spend money on weight loss solutions for 6 months60%52%50%of consumers wiling to spend money on weight loss medications for 6 months65%61%63%USDEUK%of consumers looking to lose weight in the next 12 months69%67%73%of consumers looking to lose 10 percent or more of their weight(among those looking to lose weight)62%59%55%