Promega Corporation2020年CSR報告.pdf

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1、2020 CORPORATE RESPONSIBILITY REPORTCorporate Responsibility Report2020An extremely limited quantity is printed to minimize environmental impact.We use Forest Stewardship Council paper and plant a tree for each printed report.Table of ContentsINTRODUCTIONPAGE 3Overview4Letter from the CEO5CORPORATE

2、MINDPAGE 6Purpose,Vision and Values10Investment in the Future11Conscious Leadership13Aligning Values Throughout the Supply Chain16Living in a Broader Sense of Place16PRODUCT REACH PAGE 18Customer Focus21Government and Academic Research Laboratories21Fornensics and Paternity21Pharmaceutical and Biote

3、chnology Industries24Environmental and Food Testing Laboratories26Clinical and Molecular Diagnostics Laboratories26Medical Affairs27Investment in Innovation28Quality Process and Product29PLANET AWAREPAGE 30Responding to Climate Change33Minimizing Electricity Usage and Emissions34Conserving Natural G

4、as35Building a Sustainable Future36Tracking and Reducing Effects from Product Distribution38Minimizing Effects from Business Travel40Preserving Natural Capital42Minimizing Waste42Conserving Water44Reducing Packaging Materials45PEOPLE CAREPAGE 46Nurturing Employee Creativity,Growth and Self-Actualiza

5、tion48Creating Workspaces to Inspire50Cultivating Emotional and Social Intelligence(ESI)51Providing Personal Development and Growth for Employees52PEOPLE CARE(CONT.)Building Relationships and Connections55Prioritizing Employee Health and Well-Being57Resources and Benefits that Support Employee Welln

6、ess57COMMUNITY TOUCHPAGE 60Supporting Science Around the World62Committing to Cornerstone Initiatives68Engaging In Community:Supporting Global and Local Initiatives71ADDITIONAL INFORMATIONPAGE 762019 Report Parameters77Key Indicators79GRI Index80 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWAR

7、E PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFOOVERVIEWWhile this report covers our efforts in 2019,we cant help but reference how the COVID-19 pandemic has rapidly changed our world.We are amazed to see how society has instinctively responded with“What can I do to help?”At Promega,this has meant comi

8、ng together in new,unique ways.We have doubled down on manufacturing,increasing production tenfold in some cases.Employees have volunteered to drive hundreds of miles to get product to labs faster,and cross-functional triage teams have built new connections and catalyzed new ways of working.As we co

9、ntinue to find solutions for the challenges presented by the pandemic,we remain committed to our corporate values and goals.Visit to learn how Promega is supporting COVID-19 testing and the evolving needs of customers responding to this pandemic.Additional details will be featured in our report that

10、 comes out in 2021.The following information shares how Promega employees work to make a difference for our customers,employees,and planet.You will find a spirit across the company thats driven to connect,conserve,innovate,and yesto help.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE

11、CARE COMMUNITY TOUCH ADDITIONAL INFO4|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO5|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020LETTER FROM THE CEOFor decades,we have found that working with the future

12、 in mind creates a better present.This sentiment became more popular for business at the 2019 Business Roundtable.Members of Fortune 500 companies agreed that the greatest business success will come from delivering long-term value,which requires support to the wholecustomers,shareholders,employees,c

13、ommunity,and the planet.At Promega,we are experiencing the strength of that approach,and thats been particularly clear in the COVID-19 climate.Our future-minded approach made a significant difference in our ability to deliver a strong and immediate response to a world that changed over a few weeks.W

14、eve been able to respond to the unforeseen needs of the dayour research scientists immediately engaged our technologies in exploration of a COVID-19 antibody test,the operations team increased production exponentially and hundreds of our employees transitioned to working from home.All of this happen

15、ed without sacrificing customer service or product delivery.There are a multitude of practices that successfully enabled this enormous shift:investing in an infrastructure that accommodates at least 1020 years of future planning;creating efficiencies and design in manufacturing that permits flexibil

16、ity in both manual and automated systems;developing an emotional and social intelligence sensibility to keep us strong as the days become challenging;and cultivating a company culture where all individuals knows their contributions truly matter.But even with all of this,we could not have found succe

17、ss if not for one thing.This all took time and a willingness to do what we believed best for long-term business vs a short-term bottom line.We integrated this approach decades ago.Today,we benefit from deep institutional knowledge,sincere relationships and a belief that providing high-quality materi

18、als and systems is the most efficient(and effective)approach to business.COVID-19 made us acutely aware of capability and connections of which we are tremendously gratefuland if anyone thinks a long-term approach doesnt matter in the here and nowwell,please reconsider!WILLIAM A.LINTONChairman and CE

19、OCorporate Mind INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO6|PROMEGA CORPORATE RESPONSIBILITY REPORT 20206|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Promega is flexing our muscles in the fight against colorectal cancer by supporting research a

20、nd bringing awareness to this disease.7|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFOCorporate MindIn a rapidly changing world,we reflect on how Promega contributes to scientific advancement and improvi

21、ng life around the globe.We look for qualities that stand the test of timethe sense that we can seek and co-create meaning and purpose for the larger community of customers,suppliers and stakeholders,both as an organization and for ourselves as individuals.Our business is life science,and our lives

22、are fueled by curiosity and life-long learning.Its a thread that appears in countless forms across our global organization.Founded in 1978,our company is headquartered in Madison,WI,USA,with sales branches in 16 countries,more than 50 global distributors,and three global manufacturing locations.Prom

23、ega is governed by a Board of Directors and daily operations are led by the Corporate Leadership Team and global Branch Managers.This diverse group brings wide-ranging expertise and unique cultural experience to management decisions.we find that as we develop the full potential inherent in each of u

24、s;our perceptions of limitations change:the impossibilities of yesterday become the probabilities of tomorrow.WILLIAM A.LINTONChairman and CEO1,69650+GLOBAL DISTRIBUTORS$450MREVENUE OVEREMPLOYEES17 NEW PRODUCTS LAUNCHED IN 201979NEW PATENT FILINGS IN 2019640ISSUED AND PENDING PATENTS16COUNTRIESSALES

25、 BRANCHES INOF REVENUE INVESTED IN RESEARCH AND DEVELOPMENT4,000+PRODUCTSOVER11%4,000+PRODUCTSOVERSQUARE METERS OF BUILDING FOOTPRRINT110,000PROMEGA BY THE NUMBERS:2019 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO8|PROMEGA CORPORATE RESPONSIBILIT

26、Y REPORT 2020HeadquartersR&D andManufacturingBranch OfficeDistributor INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO9|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020PURPOSE,VISION AND VALUESPurposePromega exists on an evolutionary frontier where the v

27、alues of science,business and human well-being intersect.Acknowledging these interdependencies,Promega cultivates its environment to allow employees to flourish,develop deep and enduring relationships with customers and all stakeholders and create intelligent life-science solutions.VisionPromega Cor

28、poration grows from a vision where success is measured in meaning generated for people and in relationships sustained by both value and purpose.With an eye toward a changing future,Promega continues to evolve:Our life sciences tools to accelerate discovery and realize innovative and practical applic

29、ations of advanced technology.Our commitment to improving human health.Our work environments,which support and perpetuate curiosity,self-awareness and community integration.Our capacity as a stable resource for the growth and transformation of the people and communities we touch.In essence,our visio

30、n spans across all life and moves us to act on the knowledge that we are interdependent.ValuesPromega reflects a set of living values that include:Contributing to the advancement of science for improving life in the global community.Operating as an adaptable living organism in which each element and

31、 human contribution are a vital part of a whole and capable of responding to the emerging complexities of our time.Encouraging personal development through inner and outer exploration and self-awareness practices.Recognizing that both work and home cultivate wholeness and wholeheartedness.We do this

32、 through learning,offering the best of ourselves,integrating new insights and developing inner and outer qualities that allow each individual to be present and engaged.Rewarding and acknowledging achievement through creativity,risk-taking,process improvements and innovation.Promoting adaptability an

33、d flexibility in the workplace.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO10|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020INVESTMENT IN THE FUTUREWe look at human needs to anticipate our customers wishes while providing an inspiring place for emp

34、loyees to work and support the communities in which we live.We commit to building a long-term sustainable future through investments in innovation,people,products and services,infrastructure and community outreach.In the last year,we demonstrated this commitment through investment in scientific inno

35、vation,expansion of global facilities and development of technical and leadership capabilities.Our focus in these areas means we can continue to meet customer needs and generate increased value that equates to not only financial but also meaningful growth for the goods,services,incomes,and community

36、 well-being we provide.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO11|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020An Applications Scientist works in a Promega Madison lab.In 2019,Promega announced a global collaboration with Merck to develop the

37、Promega MSI technology as an on-label,solid tumor companion diagnostic(CDx)for use with Mercks immune checkpoint anti-PD-1 therapy,KEYTRUDA.The Promega MSI Analysis System is used to identify tumors that are likely to respond well to immunotherapy.Learn more about this diagnostic and how other techn

38、ologies are making a difference in the Product Reach section.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO12|PROMEGA CORPORATE RESPONSIBILITY REPORT 202012|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Effects of Products and InnovationWe provide in

39、novative solutions and technical support to researchers,technicians and analysts in life sciences,industry and government.Over 4,000 catalog and additional custom products enable our worldwide customers to advance knowledge in the fields of genomics,proteomics,cellular analysis,molecular diagnostics

40、,human identification and applied biotechnology.In the last year,product revenue exceeded$450 million.The Product Reach section of this report expands on how our products benefit human health and advance the scientific community.Our growing investment in innovative research resulted in 79 new patent

41、 filings in 2019,bringing our intellectual property library to over 434 granted patents and 206 pending patents.In the last year,Promega launched 17 new products,fulfilling customer needs by:Aiding life science research with automated solutions.Advancing forensic DNA testing.Improving methods for st

42、udying protein structure and function.Optimizing research in clinical labs.Expediting discovery of biotherapeutics.Over 4,000 catalog and additional custom products enable our worldwide customers to advance knowledge in the fields of genomics,proteomics,cellular analysis,molecular diagnostics,human

43、identification and applied biotechnology.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO13|PROMEGA CORPORATE RESPONSIBILITY REPORT 202013|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Investments in People and PlaceOur global facilities exceeded 1.1 m

44、illion square feet or 110,000 square meters,all applying sustainable design approaches.Expansion of our branch facilities in the UK and Germany completed in 2019,providing creative workplaces and healthy spaces for our employees,customers and community outreach.In addition,construction is well under

45、way in Madison on a world-class research building and also a state-of-the-art component manufacturing facility.These buildings will add 435,000 ft2 or 40,000 m2 to the Promega footprint when completed in the next few years.For details on these expansions and environmental focus of all operations,see

46、 the Planet Aware section of this report.CONSCIOUS LEADERSHIPAt the heart of science is the understanding of the interdependent,complex and dynamic nature of systems.With nearly 1,700 individuals worldwide,this complexity is increasingly true at Promega as well.In rapidly changing environments,our l

47、eaders use their minds and hearts to flourish.We are continuously developing an environment that fosters personal connections and creates trust in the face of ambiguity to encourage conscientious and courageous action.We support the simultaneous use of intuition and the conscious awareness of emotio

48、ns,sensations,and connections when developing vision and outlook.We want a space in which everyone has an opportunity for self-awareness,personal transformation and professional development.The People Care section of this report expands on ways that Promega invests in our people and focuses on stren

49、gthening relationships.Projects implemented by Promega engineers and our facilities teams in 2019 saved over 2 million gallons of water and enough energy to power 50 homes for an enitre year.Learn more about our commitment to environmental sustainability in the Planet Aware section.The Feynman Cente

50、r on the Promega Madison campus.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO14|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Promega global general managers gather in Madison,WI.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COM

51、MUNITY TOUCH ADDITIONAL INFO15|PROMEGA CORPORATE RESPONSIBILITY REPORT 202015|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Advancing DiversityAs a global company,we acknowledge and honor the fundamental value and dignity of all individuals and pledge ourselves to creating and maintaining an environme

52、nt that respects diverse traditions,heritages,experiences and perspectives.Being relevant requires continued focus on building diversity and inclusion.Increasing minority and gender diversity is a goal for hiring and promotion.Women represent approximately 47%of employees worldwide and occupy 39%of

53、management positions.With offices in 16 culturally diverse locations,we benefit from the unique cultures and experiences of all employees.Respecting Human RightsAs a member to the UN Global Compact,Promega follows all regulations regarding employment and has zero tolerance for violations of human ri

54、ghts.We are committed to upholding and advancing The Universal Declaration of Human Rights by developing productive business relationships around the world to continue working cooperatively among different customs and cultures.Issues that we take very seriously include:Protecting children from explo

55、itation.Protecting all workers from modern slavery.Paying at least minimum wage.Safe working conditions.Promega complies with all local workplace regulations and ensures that our employees and community members are treated with respect and dignity.We hold the same expectations for our suppliers and

56、look to align with organizations that uphold international human rights and labor standards.Our active and continuously developing Emotional and Social Intelligence(ESI)initiative emphasizes connection and encourages employees globally to grow and become their best.ESI skills support an environment

57、that respects diverse traditions,heritages,experiences and perspectives.Learn about all the ways Promega supports employees in the People Care section.Promega Corporation and branches in Spain,Singapore,France,Switzerland,Germany and the Netherlands support the International Genetically Engineered M

58、achines(iGEM)competition for emerging scientists.Learn more about this and other efforts to give back in the Community Touch section.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO16|PROMEGA CORPORATE RESPONSIBILITY REPORT 202016|PROMEGA CORPORATE R

59、ESPONSIBILITY REPORT 2020Prioritizing Anti-CorruptionPromega aims to operate with the greatest integrity and has zero tolerance for corruption or bribery.This commitment to anti-corruption is communicated to all employees in a Code of Conduct and additional training is provided to managers and emplo

60、yees in purchasing or sales departments.ALIGNING VALUES THROUGHOUT THE SUPPLY CHAIN Promega recognizes the effect and importance that suppliers have in the scope of our Corporate Responsibility and forms partnerships with companies who have similar commitments.Our Supplier Code of Conduct outlines o

61、ur expectations relating to business ethics,labor,health and safety,and environmental responsibility.This document is shared with new and existing suppliers to encourage collaboration in these areas.A focus on sourcing from local suppliers also supports local communities and reduces environmental ef

62、fects from shipping.LIVING IN A BROADER SENSE OF PLACE“Place”is not singular at Promega.Our sense of place covers all touch points by integrating work,home and community.We understand how any one touch point can impact the others:A tough day at work can mean an irritable evening at home,and poor com

63、munity connections can leave gaps resulting in misunderstanding.By living with regard to the interactions and dependencies of each of these“places,”we can become more fully fueled in ourselves,our work and our understanding of each other.Just as importantly,we open ourselves to greater learning and

64、innovation for the future.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO17|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Within the context of each place(work,home,community),we find complexity.For example,Promega engagement in community includes mul

65、tiple approaches like opening opportunities for employees to give back on their terms,supporting our emerging scientists around the world and fostering greater creativity and learning.Stories on many of these actions are shared throughout this report.The benefits of this work reach far beyond good w

66、ill.Our work brings growth and real impact to the community bottom line.In the state of Wisconsin alone,a third-party economist estimates that Promega has an annual economic impact of over$1 billion each year.Growth and success of any business,especially one the size and scope of Promega,can have a

67、positive ripple effect in communities,which comes back again to support long-term,sustainable practices.Creating such a positive cycle happens when we are connected and share our place with all stakeholders.Promega was recognized by the Wisconsin Economic Development Association(WEDA)for making sign

68、ificant contributions to Wisconsins economy.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO18|PROMEGA CORPORATE RESPONSIBILITY REPORT 202018|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Product ReachA Promega scientist at the companys Rosalind Frankl

69、in Center production facility in Madison,WI.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO19|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Product ReachDeveloping innovative solutions to meet the complex and ever-changing needs of our customers begin

70、s with listening.We build solid relationships with our customers by investing time to truly understand their work and anticipate their needs so we can problem solve together.Our alliance with them,coupled with determined scientific exploration and flexible manufacturing capabilities,enable us to sup

71、port our customers in their work to improve the world in profound ways using science.Every day,research scientists,technicians,and analysts in laboratories and industrial facilities around the world rely on our products and technical expertise to succeed in the work they undertake.With high-quality,

72、reliable products at their disposal,researchers,applied scientists,clinical practitioners,forensic analysts,quality assurance personnel and others have more freedom to focus on specific questions at the forefront of scientific discovery.This results in the acceleration of research discovery,better h

73、ealth care,and more consistent justice.With passionate dedication to emotional awareness and intellectual execution,people at Promega connect with each other and with scientists around the world to co-create solutions to the most relevant problems in life science.PONCHO MEISENHEIMERSenior Director,R

74、esearch and Development19|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Academic/Government25Pharma/Biotech28ClinicalDiagnostics24Applied and Enviro Testing3GeneticIdentity20Sample Analysis SolutionsNucleic Acid Quantification Amplification NGS/Sequencing Instruments STR AnalysisProtein Analysis and M

75、olecular CloningCloning Protein Expression and Purification Mass Spectrometry ImmunoassaysCellular Reporting and SignalingGenetic Reporters Protein Reporters Target Engagement Cell Signaling Instruments BioassaysCell Health and Functional AnalysisReal-Time Assays Energy Metabolism 3D Analysis ADME I

76、nstruments Protein DegradationSegment ServicesCustom and OEM Manufacturing Custom Assays Platform Integration Application DevelopmentSample Preparation SolutionsCore Technologies%Breadth of CapabilitiesScientific SegmentsManual to Automated Nucleic Acid Purification Instruments INTRODUCTION CORPORAT

77、E MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO20|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO21|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020CUSTOMER FOCUSForensics and Pa

78、ternity Laboratories Forensics and paternity testing laboratories deal with unrelenting caseloads and tight turnaround times.Dependable results,fast throughput and reliable product supply are critical in this setting.Forensic labs use limited,often challenging samples to develop investigative leads

79、from crime scenes.Sexual assault kits and property crime evidence are some of the more challenging samples for labs to process.Forensic labs process large numbers of reference samples to populate reference databases that help law enforcement connect arrestees to other crimes,with the goal of identif

80、ying possible repeat offenders.Ongoing testing of the rape kit backlog has identified over 1,000 suspected serial rapists in the United States alone.In addition to analyzing evidence collected at crime scenes,forensics labs help bring closure to families whose loved ones are missing or lost in mass

81、disasters,and even help exonerate those who have been wrongly convicted of a crime.These researchers and analysts require optimal and reliable results from valuable and often irreplaceable evidence samples.We have worked with forensic and paternity laboratories for more than 30 years and support the

82、ir challenging workflow procedures by providing advanced technologies for efficient DNA extraction through discriminating STR analysis.With the emergence of new tools and technologies on the horizon,labs will be able to gain more information from challenging sample types,save time with increased sam

83、ple processing capacity,triage samples for more efficient workflows,solve more cold cases with investigative genealogy and database searches,and even bring the entire workflow to the scene of the crime or event.We have worked with forensic and paternity laboratories for more than 30 years and suppor

84、t their challenging workflow procedures by providing advanced technologies for efficient DNA extraction through discriminating STR analysis.Government and Academic Research LaboratoriesIn the face of increasing pressure and demands,todays academic and government researchers work on the front line of

85、 discovery.They require the newest available tools with enhanced sensitivity and specificity to address more complex biological questions compared to methods used just a few years ago.Promega continues to develop and improve technologies from next-generation nucleic acid isolation and PCR to advance

86、d assays for cellular biology,metabolism,3D cellular structures and organoids,protein manipulation and CRISPR knock-ins for tagging cell lines.To help modern researchers successfully publish their results,fulfill their research programs and nurture carefully planned careers,Promega is committed to d

87、eveloping the most advanced bioassays,target engagement and protein degradation tools.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO22|PROMEGA CORPORATE RESPONSIBILITY REPORT 202022|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020CSI SAVANNA:OVERCOMING

88、 THE CHALLENGES OF ISOLATING HUMAN TOUCH DNA FROM POACHED RHINOCEROSRhinoceros numbers are on a steep decline,from 500,000 in the 20th century to an estimated 30,000 alive today.Poaching is the main driver for this decline,which comes from consumer demand for rhino horn.Although the trade of rhino h

89、orn is banned,the demand remains high.With prices averaging$60,000 per kg,the sale of rhino horn on the black market is a lucrative venture.To preserve rhinoceros species,poaching must be stopped.Poaching cases can be extremely difficult to investigate and prosecute due to the nature of the evidence

90、 available at the scene.Current practices use rhino DNA profiling to match horns with carcasses,but due to low genetic diversity among some rhino species there is decreased confidence in matching a horn to a specific animal.Human DNA profiling using touch DNA from poachers could be a better approach

91、.Humans have very unique DNA profiles,increasing chances of linking a poacher to the scene.However,sample collection challenges exist with this approach that need to be overcome.Human touch DNA samples have low abundance of DNA,and the dry,rough,dirty surface of rhino skin compounds the recovery iss

92、ue.Optimal sampling techniques combined with sensitive extraction and DNA amplification technologies will therefore be needed to establish human DNA profiles.Researchers from the University of the Free State in South Africa are investigating various methods of touch DNA recovery from rhino back,rump

93、,ears,legs,head and horns.Several Promega technologies designed for low-level DNA samples have been instrumental in their work.The Promega Casework Direct Kit,designed for extraction from low-abundance DNA samples,is being used to prepare lysates for downstream PCR amplification.The sensitive PowerP

94、lex ESI 16 System and Direct Amplification from swabs method is being used to generate the DNA profiles from these low-abundance touch samples.Preliminary results have uncovered mixed and partial profiles,generating hope that human touch DNA could one day be an essential tool in linking or excluding

95、 suspects involved in these crimes against wildlife.Forensic analyst swabbing the head and ears of a rhino during a dehorning procedure in Port Elizabeth.Rhinoceros in South Africa.Forensics INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO23|PROMEGA

96、CORPORATE RESPONSIBILITY REPORT 2020MEETING THE SCREENING CHALLENGE ON PROTEIN:PROTEIN TARGETS TO UNDERSTAND MALFUNCTION OF HEALTHY CELLSBillions of new cells are made in the body every day,replacing worn-out,dead or damaged cells and keeping us healthy.Cells multiply by dividingan existing cell spl

97、its in half to create two new ones.This process is very tightly organized so that new cells are made only when and where they are needed.Faults in key genes controlling cell division(known as oncogenes)make cells multiply out of control,leading to cancer.The Oncogene Biology Laboratory headed by Jul

98、ian Downward at the Francis Crick Institute in the UK investigates how the molecular signals received by cells make them grow and multiply,and how faulty signals lead to cancer.They focus on oncogene function in healthy cells and find out what happens when they go wrong.Some types of cancer can even

99、 become addicted to certain oncogenes,relying on just one faulty gene to drive their unchecked growth.Dr Soly(Mohammed)Ismail,a post doctorate researcher within the Oncogene Biology Laboratory,is particularly interested in a target known as Ras.This oncogenic protein is found to be faulty in almost

100、30%of human cancers,including bowel,pancreas and lung tumors,and so it is a very important target to understand.Much work has been done on inhibitors of Ras,specifically those that inhibit the Ras-Raf and Ras-P13K protein:protein interactions.In the past 10 years,the Oncogene Biology Laboratory has

101、shown that inhibition of the Ras-P13K interaction has a significant effect on tumor initiation,development and maintenance so finding out how to switch off Ras signaling could be a powerful way to treat cancer.Solys aim is to discover and characterize specific inhibitors that could block RAS/P-I3K a

102、nd RAS/RAF for future targeted therapies.Targeting the interaction of proteins represents a particular challenge for drug screening largely due to the strength by which they bind or their solubility.Promega NanoLuc Binary Technology(NanoBiT)was originally developed to detect protein:protein interact

103、ions in live mammalian cells.Instead Soly successfully adapted this NanoBiT cellular assay into a biochemical,cell-free format using mammalian cell lysates.The NanoBit Biochemical Assay now offers an attractive tool for drug screening against challenging protein:protein interaction targets,including

104、 the interaction of RAS with PI3K.Research LaboratoriesDr.Soly Ismail,Postdoctoral Fellow,Francis Crick Institute23|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Pharmaceutical INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO24|PROMEGA CORPORATE RESPON

105、SIBILITY REPORT 2020Pharmaceutical and Biotechnology IndustriesScientists within the pharmaceutical industry are continuously developing new small-molecule drugs that can enter cells easily and affect specific target proteins.Targeted cancer therapies that block the growth and spread of cancer by in

106、terfering specifically with the diseased cells,but not normal healthy cells,are one example where small-molecule drugs are used therapeutically.At early phases of drug development,researchers may screen more than 100,000 compounds at once to identify leads that can be further optimized and turned in

107、to new drugs.The availability of high-throughput-compatible,reliable and predictable assays serves a crucial step toward discovering new safe and effective drugs.Promega has developed a broad portfolio of assay reagents that meet the needs of these pharmaceutical researchers and have been used widel

108、y during various phases of drug discovery and development.For example,our NanoBRET Target Engagement Assays allow researchers to quantitatively measure the interaction between a molecule and a protein in live cells reliably in a high-throughput manner.This is a significant advancement as these cellu

109、lar assays can better predict compound performance.In addition to common drug targets like kinases,this NanoBRET Target Engagement technology has also been applied to CRISPR-Cas9 gene edited cells to help identify drugs that can lead to oncoprotein degradation.AIDING IN DRUG DEVELOPMENT AND DISCOVER

110、YThe cell is the basic structural and biological unit of all organisms.How our cells function,including if they divide or die,is tightly controlled by a large collection of proteins called kinases.When these proteins mutate and their signaling capabilities become faulty,cell growth and division can

111、be negatively impacted and diseases such as cancer can occur.Live-cell model systems are an important tool for laboratory researchers in their quest to develop and evaluate cancer drugs against target kinases.The most helpful live-cell models represent the endogenous biology,or true-to-life conditio

112、ns,observed within the human body.Studying potential drug compounds in a live cell is a relatively new practice.Scientists typically use biochemical methods with enzymes purified from ruptured cells,but this testing approach isnt always relevant to how drugs behave in the body.Live cells,with the en

113、zymes inside,would provide researchers a more predictive model of drug behavior.Obtaining this more predictive data in the early stages of drug exploration will allow researchers to move through R&D faster and continue to advance human health.Promega scientists developed a unique way to study kinase

114、s using an energy transfer technique and specially designed cell-permeable detection probes that enable testing in a live-cell environment.The NanoBRET TE Intracellular Kinase Assays use Bioluminescence Resonance Energy Transfer,or BRET,to measure the binding of the drug to the kinase.This new techn

115、ique helps researchers determine if the drug gets into the cell,if it interacts with the intended target,and how long it stays bound despite other things in the cell trying to bump it off.With this new live-cell approach,pharmaceutical researchers can arm themselves with the comprehensive data they

116、need for a more complete picture of kinase target effects as they move to the next phases of development.Artists conception of NanoBRET TE Intracellular Kinase Assay at work inside a live cell.Environmental Testing INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH AD

117、DITIONAL INFO25|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020XYLELLA FASTIDIOSA:SEEKING EARLY DETECTION OF A MICROSCOPIC THREAT TO AGRICULTURE ECONOMIES Agriculture is the lifeblood of human existence.We rely on the cultivation of plants as a source of nourishment for our bodies and the generation of

118、 plant-derived products to support our economies.Agriculture offers a connection to the land and a way of life for generational growers.Destruction of our agricultural ecosystems can have devastating impacts on our livelihoods.Sadly,a global agricultural threat is growing at an alarming rate,and the

119、 causative agent is a microscopic one.Xylella fastidiosa is a bacterium that infects and reproduces in xylem,a tissue found within vascular plants that transports water and nutrients from roots to stems and leaves.The bacterium is mainly spread by insects feeding on plants.Infection with this bacter

120、ium deprives plants of the nutrients they need,resulting in starvation and death.Most plants die within 12 years of infection and there is currently no cure.Globally,infection with Xylella has affected over 20 million olive trees in Italy and other parts of Europe,bringing the olive oil industry to

121、its knees.In Brazil,the majority of orange trees have been killed in efforts to control the disease.In the US,Spain and Middle East,almond trees are infected.With such immense socio-economic impacts at stake,quick detection of this bacterium can go a long way to manage the spread of the disease.Labs

122、 are exploring new ways of detection,and DNA purification from plants is becoming one of the key aspects of analysis.Promega is positioned to help in the quest for early detection and continuous monitoring of X.fastidiosa infection.We provide tools for DNA extraction and automated processing that ca

123、n meet the needs of plant pathogen testing labs as the number of samples continues to grow.Together with the laboratory community,we have developed plant and insect DNA extraction methods that are robust and reliable for use with a variety of materials.The Maxwell line of instruments provides a walk

124、-away,automated approach to extracting plant DNA from up to 48 samples simultaneously.When used together,this system provides purified DNA to plant pathogen testing labs in under one hour for subsequent immediate use in qPCR and other molecular detection methods.Over 20 million olive trees in Italy

125、and other parts of Europe are infected with Xylella.25|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO26|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Water treatment facilities and desalination plants test

126、 water quality and biofilm formation to reduce energy consumption and improve plant operational efficiency.By partnering with these facilities,we have been able to improve our luminescent bacterial detection assay for specific use with water sampling to help with industrial processes like biocide do

127、sage and timing for water cooling systems.Promega Water-GloTM microbial analysis uses bioluminescence to measure the amount of adenosine triphosphate(ATP)in drinking water,desalinated water and other samples to monitor water quality.Clinical and Molecular Diagnostics LaboratoriesIn 2020,Promegas imp

128、act on the clinical diagnostic world was demonstrated through our rapid and robust response to COVID-19 testing.Promega solutions supported COVID-19 diagnosis in over 25 million samples around the globe in the first quarter alone.GoTaq Probe 1-Step RT qPCR System was added to the CDCs 2019-Novel Cor

129、onavirus Real-Time RT-PCR Diagnostic Panel Emergency Use Authorization on March 31,2020,further expanding testing options and capacity for labs in the United States.Promega Viral RNA sample extraction solutions,ranging from manual to high throughput,provided options for clinical labs processing samp

130、les in a time of unprecedented demand on public health labs.Promega custom manufacturing supplies critical reagents that are part of 15 COVID-19 diagnostic tests marketed by other diagnostic manufacturers.OncoMate MSI CE IVD became available to the European market in March of 2020.This new molecular

131、 diagnostic tool enables labs to determine microsatellite instability status in tumor tissue,an important step in diagnosing and treating cancer patients.Until 2015,MSI testing was part of a workflow to determine if a patient tumor was hereditary,enabling relatives to have preventive testing.More re

132、cently,in addition to hereditary tumor testing,MSI Dx Analysis System status is recognized as a key factor Environmental and Food Testing Laboratories Demand for food and water testing is increasing as laboratories seek rapid,reliable solutions to ensure products are safe and food ingredient claims

133、are authentic.Biotechnology offers tools for testing labs to detect bacteria or other contaminants in food,water or plants.From GMO testing and pathogen detection in food to water quality and contamination analysis,assays need to satisfy the requirements of food and water testing laboratories,includ

134、ing sensitive detection of unwanted microbes and undeclared ingredients.To screen plants for GMOs,analyze food for pathogen contamination or authenticate ingredients,DNA must be extracted from the samples.The resulting DNA needs to be pure enough to work in PCR-based analysis,the method most food te

135、sting labs use for detection.In Europe,Promega DNA purification reagents have become a reference standard in authenticity determination of meat products,and European Union Reference Laboratory for Animal Proteins in feeding stuffs(EURL)has developed a Standard Operating Procedure for DNA extraction

136、based on our purification chemistry.In addition,our Maxwell RSC PureFood GMO and Authentication Kit was recently selected by the European Reference Laboratory on GMO Food and Feed Testing for developing new Standard Operating Procedures for food DNA extraction,influencing food companies to use Prome

137、ga products as part of their routine quality control testing.Our Environmentally Preferable Products require less packaging,include fewer hazardous components and generate less waste to support sustainability efforts of customers.To learn more,visit:P Diagnostics INTRODUCTION CORPORATE MIND PRODUCT

138、REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO27|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Medical AffairsAccelerating the impact of research on the practice of improving human health and well-being is the highest priority for the Medical Affairs team.Our dedicated team of scientif

139、ic experts focuses on providing technical and scientific support to the clinical research and healthcare communities around the world.Medical Affairs plays a critical role in the interchange of scientific and medical knowledge as it relates to patient care.We engage with key scientific leaders and c

140、linicians to provide perspective and input on the evolving needs for medical information,education and support of new product development efforts.From infectious disease to oncology,impactful science and emerging resilience tie Medical Affairs to our global community.SUPPORTING TAILORED TREATMENT WI

141、TH TUMOR CELL TESTING Promega first developed the Microsatellite Instability Analysis(MSI)system over fifteen years ago,but the advent of immune checkpoint inhibitor therapy has revealed new applications for the technology.Tumors with defects in the expression of functional mismatch repair(MMR)prote

142、ins often have somatic mutations that produce“foreign”proteins that can be detected by the immune system.As a result,these tumors are effective at priming an immune response and subsequently susceptible to immunotherapies.MSI analysis can identify the presence of mismatch repair(MMR)deficiency,and t

143、hus predict a positive response to immunotherapies such as immune checkpoint inhibitors.In late 2019,Promega announced a global collaboration with Merck to develop the Promega MSI technology as an on-label,solid tumor companion diagnostic(CDx)for use with Mercks immune checkpoint anti-PD-1 therapy,K

144、EYTRUDA(pembrolizumab).KEYTRUDA,like other immune checkpoint inhibitors,works by activating the bodys own immune system to identify and attack tumor cells.The Promega MSI technology was used in clinical trials to identify tumors that were likely to respond to this type of treatment.The global collab

145、oration will initially seek regulatory approval for the Promega OncoMate MSI Dx Analysis System in the United States and China.Plans to seek approvals in additional territories may follow.In March 2020,the OncoMate MSI Dx Analysis System(OncoMate MSI)also received CE marking as a new in vitro diagno

146、stic(IVD)medical device in Europe.Promegas research-use-only MSI technology has been validated in labs around the world to characterize solid tumor MSI status.As scientists understand more about the biology of MSI-high tumor cells,even more tailored and effective therapies can be developed against t

147、umors expressing the MSI biomarker.in determining if patients are eligible for a new and effective class of oncology drugs,PD-1 inhibitors,that are having dramatic results in extending the lives of late-stage cancer patients.In November of 2019,Promega signed a global companion diagnostic developmen

148、t agreement with Merck to further develop the OncoMate MSI assay as a companion diagnostic for Keytruda,a PD-1 inhibitor.Clinical trials are underway in China for this indication.27|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUN

149、ITY TOUCH ADDITIONAL INFO28|PROMEGA CORPORATE RESPONSIBILITY REPORT 202028|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020INVESTMENT IN INNOVATIONTo sustain our contributions to scientific exploration and application,Promega invests in the development and discovery of new technologies.In 2019,over 11%o

150、f total revenue was allocated to research and development.Research is not solely focused on the development of new products;our Advanced Technology Group and a group funded by the Federal Government perform basic research.Our growing investment in innovative research resulted in 79 new patent filing

151、s in 2019,bringing our intellectual property library to over 434 granted patents and 206 pending patents.Promega research scientists had 21 scientific papers published in the last year.We also work with academic institutions and other entities to license and develop promising technologies.640TOTALPa

152、tentsIssued and Pending ApplicationsCELLULAR ANALYSIS479GENOMICS26GENETIC IDENTITY AND OTHER28PROTEOMICS36INSTRUMENTATION71 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO29|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020QUALITY PROCESS AND PRODUCTProm

153、ega Corporation has a long history of supporting our customers with high-quality products,services and information.Promega Madison,WI,USA,was first certified to International Organization for Standardization(ISO)for quality management systems in 1998,and our commitment continues with our current ISO

154、 13485 and ISO 9001 certifications.The ISO series of quality management system standards are developed and maintained by the International Organization for Standardization.An organization achieving ISO certification has demonstrated to a third party that the organization meets all requirements of th

155、e standard and has implemented a quality system capable of developing,manufacturing,testing and delivering high-quality products around the world.ISO certification assures our global customers that Promega is committed to quality and has established reliable and effective processes.ISO certification

156、 exemplifies commitments to our customers,to our business,and to all those who rely on and benefit from the use of our products.Currently,16 Promega locations around the world are certified to meet the requirements of ISO 9001,ISO 13485 or both.In February 2016,ISO 18385:2016 was published as the fi

157、rst international standard specific to the forensic manufacturing community.In 2017,Promega became the first major forensic manufacturer to achieve third-party certification of the published ISO 18385 standard to minimize the risk of human DNA contamination in products used to collect,store and anal

158、yze biological material for forensic purposes.Promega products manufactured in alignment with the ISO 18385 standard include a“Forensic Grade”certification logo.GOING ABOVE AND BEYOND FOR OUR CUSTOMERSI am so thankful and proud to work for Promega and with such amazing co-workers!We received a call

159、from a clinical lab late yesterday afternoon,after our corporate office had closed.The lab was in a pinch with clinical samples to run on their Maxwell AS3000 Instrument.Their external computer had crashed,and they could not get the replacement computer to connect to the instrument.They had pending

160、patient reports that they needed to release to clinicians and needed to run additional samples today,on Christmas Eve.Team members from multiple departments globally connected late into the evening to begin the troubleshooting and devised a plan to help this lab before Promega closed for the holiday

161、s.I visited the lab the next day to trouble-shoot on-site with the remote support of several Promega team members.We were all taking time away from family Christmas eve celebrations.After trying multiple different things over several hours,we were able to access the patient sample run data files and

162、 print them to pdf per their SOP.One of the runs was a viral screen of a child pending results.The lab was able to move forward per their SOP and release the results to the doctors.The level of support this lab felt from Promega was astounding.We were literally jumping for joy when we were successfu

163、l.They are back in business and will be running samples through the holiday.The gratitude and joy the customers and I felt were awesome.Promega co-workers truly are a family and a support network that can always be relied on!This would not have worked without everyones input and tenacity.Amy Parman,

164、Sr.Regional Manager with gratitude to Rebecca Roberts,Brian Leininger,Jessica Rossol-Allison,Promega Korea,Promega Australia INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO30|PROMEGA CORPORATE RESPONSIBILITY REPORT 202030|PROMEGA CORPORATE RESPONSIB

165、ILITY REPORT 2020Planet AwareSustainability is integral to how we design and build facilities with our new Research and Development Center being projected to use 60%less energy per square foot than our existing research facility.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMM

166、UNITY TOUCH ADDITIONAL INFO31|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Planet AwareIn 2019,Promega realized gross reductions in electricity,natural gas and water while also achieving all environmental improvement targets set for the end of 2020.As indexed to revenue,we have seen carbon emissions

167、reduce by 13%and water use reduce by 27%since 2015.These accomplishments are thanks to the efforts of our people,whether it be individuals improving efficiencies in operations or employee-lead teams enhancing a culture of sustainability.One of the hardest things for people to wrap their heads around

168、 tends to be the idea that small wins add up to big victories.However,if we want to make a big difference for the future of our planet and its people,we have to overcome our indifferences towards so many small things in life.MAURO CIGLIC General Manager,Promega AG31|PROMEGA CORPORATE RESPONSIBILITY

169、REPORT 2020Status Toward 2020 GoalsALL AHEAD OF TARGETElectricityWater10%GoalGas10%GoalWasteDistribution2%Goal15%Goal5%Goal10%GoalCarbon13%15%12%15%6%In 2019,Promega realized gross reductions in electricity,natural gas and water while also achieving all environmental improvement targets set for the

170、end of 2020.Reductions and targets are indexed to revenue and over a 2015 baseline.27%INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO32|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020As we enter a new decade,we hold both hope and uncertainty about the

171、future of our world.From climate change to global pandemics,we are facing urgent issues.In response,Promega hosted the first ever sustainability summit for our European branches to identify actions and environmental targets for the upcoming decade.All regions globally will evaluate and commit to the

172、 next generation of environmental goals in the coming year.During this process we take inspiration from the United Nations approach to the Sustainability Development Goals and acknowledge that the Decade of Action will require mobilizing everyone,urgency and ambition,and supercharging ideas in actio

173、n.313129545551201052110720100295119999429471896201520192020GoalFuel CombustionPurchased ElectricityBusiness TravelOutgoing DistributionWater UsagePaper UsageCarbon FootprintTons of CO2 Per Million USDFigure 1.Global carbon footprint as indexed to revenue has reduced by 13%since 2015.Carbon is calcul

174、ated from fuel combustion(scope 1),purchased electricity(scope 2),and business travel,outgoing distribution,water usage and paper usage(scope 3).INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO33|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020RESPONDING

175、 TO CLIMATE CHANGEPromega prioritizes greenhouse gas reduction from all global operations.In evaluating emissions,we consider fuel combustion,purchased electricity,indirect emissions from business travel,outgoing distribution,water usage and paper usage at all Promega locations worldwide(see Figure

176、1).We are currently ahead of our 2020 target for carbon emissions thanks to actions to reduce impacts from energy usage.Global CarbonFootprint CompositionElectrical UsageNatural GasRail TravelWaterAir TravelAutomobile TravelPaperDistribution52%20%0%0%7%2%0%19%ElectricityThousands of kWh Per Million

177、USD201579.781.47467.7201973.22020Goal78.1 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO34|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 Connecting our R&D facility to a more efficient central chiller plant has delivered savings over 500,000 kWh eac

178、h year.In 2020,we will extend our central plant to additional facilities to further optimize energy requirements.Renewable energy is a key strategy to limit greenhouse gas emissions from operations.In 2019,our largest solar array was installed on the newly renovated Feynman parking ramp.This system

179、will generate 562.5 kW and quadruple our current renewable energy production.This array alone will generate enough energy to power over 100 homes each year.We also have committed to large scale photovoltaic arrays on the Feynman Center and the new R&D center in 2020.Additional facilities that use re

180、newable energy sources such as photovoltaic and geothermal currently include:Promega GmbH in Waldorf,Germany Promega UK in Southampton Promega Italia in Milan Promega Biotech Ibrica in Alcobendas,Spain Promega Biotech AB in Stockholm,Sweden Promega AG in Zurich,Switzerland Promega Brazil in Sao Paul

181、o The Aviation Operations building in Madison,WI,USA The da Vinci facility in Madison,WI,USAMinimizing Electricity Usage and EmissionsIn the last year,gross electricity usage decreased by 2%even with an increase in building footprint.This saved over 524,000 kWh,the equivalent of the electricity used

182、 by nearly 50 homes annually.Transitioning operations to more-energy efficient-facilities,projects to improve energy efficiency and the daily efforts of all employees worldwide made these reductions possible.Electricity usage contributes to over 50%of our carbon emissions and minimizing these effect

183、s is a focus at all Promega locations.To this end,we invest in energy efficiency,generate electricity from photovoltaic panels and purchase electricity from renewable sources.Recent highlights include:Company-wide initiatives to incorporate high-efficiency LED lighting continued in 2019.Renovations

184、were completed at three more facilities last year,affecting over 1,000 lamps and saving over 117,000 kWh annually.gross electricity usage decreased by 2%even with an increase in building footprint.This saved over 524,000 kWh,the equivalent of the electricity used by nearly 50 homes annually.Figure 4

185、.Natural gas usage as indexed to revenue.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO35|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Natural GasTherms Per Million USD20153,44420163,39120173,32120183,28720192020Goal3,1003,025Conserving Natural Gas

186、In the last year,gross natural gas usage reduced by 2%or by 8%as indexed to revenue.Natural gas is our largest source of direct air emissions and our third largest source of overall emissions.Natural gas is used primarily at manufacturing sites for heating and production-related processes.Geothermal

187、 wells,solar water heaters and heat capture technology help minimize heating requirements and related emissions.Promega was a Distinguished Performer Award winner in the sustainability category as part of the 2019 Wisconsin 75 list recognizing the largest privately held companies in the state.The re

188、cently completed parking garage provides clean energy to the campus and electric vehicle charging.Geothermal wells,solar water heaters and heat capture technology help minimize heating requirements and related emissions.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOU

189、CH ADDITIONAL INFO36|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Building a Sustainable FutureIn times of rapid growth,we look to the future with optimism while also assuring that our expansion is sustainable.The Promega Global Facilities Planning Team emphasizes environmental stewardship and long-t

190、erm planning.Each building is designed to meet ambitious sustainability goals,and innovations incorporated into one project inform the next.In 2019,we finished construction on two new buildings in Europe and made progress on two important facilities at our headquarters in Wisconsin.UK Branch Office

191、Opens in Southampton,UKIn September,the employees of Promega UK moved into a new 1,700m2(18,000 ft2)building featuring wet and dry training labs,a product storage facility,office spaces and even a small gym for use by staff.During the five years of planning that went into the new building,the team f

192、ocused on conserving energy and water while reducing carbon emissions.They included features such as ground source heating,which is cleaner and more efficient than gas-or oil-powered heating.The resulting facility is built to exceed BREEAM Excellent standards,an assessment used in the UK to certify

193、the sustainability of buildings.In the few months it has been occupied,this new facility has been 45%more energy efficient per cubic meter than the previous facility.Promega GmbH Relocates to Waldorf,GermanyIn November,Promega GmbH relocated from Mannheim to Waldorf,Germany.At 14,000 m2(150,000 ft2)

194、,the new facility is the largest outside of Madison,WI,and brings together all Promega teams previously located in Mannheim,including the largest non-US branch office,the European Distribution Center(Euro Hub),the European Instrument Center and Terso Europe.The building is operational,but finishing

195、touches are still being completed.The facility features a ground source heat exchange system for heating and cooling,solar photovoltaics,green roof and a small onsite lake for grey water usage.Most of the office spaces are lit by natural lighting,and there are plenty of green spaces inside to improv

196、e air quality.Care went into preserving the environment around the building,and lumber from trees that needed to be removed during construction is now being used to build a bike shed,which the team hopes will encourage more employees to bike to work.Electric vehicle charging stations are also being

197、added.The new home of Promega UK has been designed to exceed BREEAM standards for excellence in sustainability.Promega GmbH in Waldorf,Germany“We take pride in the details and quality.and in preserving nature and making sure our building is a place where people like to be.”ANETTE LEUE,Digital Market

198、ing Manager of Promega GmbH INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO37|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020New R&D Building in Madison,WIThe new Promega Research&Development building is under active construction with the structure mos

199、tly complete.When finished,the building will house all R&D groups,as well as Scientific Applications&Training and Integrated Systems&Engineering.At approximately 26,600 m2(287,000 ft2)this building will house more than double the amount of lab space Promega currently occupies.The new R&D building is

200、 projected to use 60%less energy per square foot than the existing R&D Center.The thermal slab will provide heating and cooling from a ground source heat exchange system,saving energy.Additionally,the whole perimeter of the building will be wrapped in a double-walled facade,consisting of an interior

201、 concrete wall and an exterior brick wall,separated by three feet of air space.The result is like a Thermos of coffeethe space between the two walls creates a buffer to absorb some of the heat that would otherwise be gained or lost to the environment.The glass panes in both walls can also be opened

202、when weather permits,which will provide natural ventilation and further alleviate the energy requirements of temperature control.A water reclamation system is also expected to save over 1,000,000 gallons annually.Inside,the space has been designed to foster creative lab and desk spaces while maximiz

203、ing efficiency.Wet labs are surrounded by dedicated instrument rooms,and all lab benches are modular.The cloverleaf shape of the building gives each research group its own area with plenty of space to work and grow.With a new cafeteria serving locally grown food,a gymnasium and a sound therapy studi

204、o,the building balances efficient workspaces with plenty of areas for employees to recharge.Component Manufacturing Center in Madison,WIWhen the Component Manufacturing Center opens in 2021,it will house newly developed product manufacturing lines in a 14,600 m2(158,000 ft2)facility only a few miles

205、 from the Promega global headquarters.This facility will complement existing manufacturing capacities in Madison and California by supplying small-molecule components for use in other manufacturing processes.The groundbreaking ceremony took place in June 2019 and construction is well underway.The bu

206、ilding is scheduled for completion in the second quarter of 2021.New Research&Development Building in Madison,WIComponent Manufacturig Center groundbreaking in 2019 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO38|PROMEGA CORPORATE RESPONSIBILITY R

207、EPORT 2020Helix carbon offsets support the Blandin Improved Forest Management Project38|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Tracking and Reducing Effects from Product Distribution We look for ways to reduce air emission from outgoing product distribution with continuous focus on decreasing t

208、he size and weight of packaging materials.This approach,combined with using efficient modes of transportation,reduces emissions and maintains our quick and safe service.As a result,we have seen a 26%reduction in distribution emissions as indexed to revenue in the last 10 years.Over the last few year

209、s,we have transitioned to smaller shipping boxes and made packaging improvements that minimize weight,optimize dry and gel ice requirements and use more sustainable materials.To understand the indirect emissions from outgoing shipments,data was collected from Promega-owned global distribution hubs o

210、n weight,distance and mode of transportation.Ambient Shipping InitiativeIn the last year,Promega launched the Ship Ambient Project to transition select product lines that currently ship on dry or gel ice to room temperature or ambient shipping.Rigorous testing of DNA molecular weight markers shipped

211、 at room temperature showed no changes to product performance.The first phase of this project launched in early Distribution EmissionsTons of CO2 Per Million USD20152020Goal201921.120.319.319.820.018.9 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO

212、39|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Net Zero Emissions from our Helix On-Site Stocking SystemOur state-of-the-art,on-site inventory management system called Helix further reduces emissions through precise consolidated restocking shipments.The Helix program uses RFID technology that tracks

213、 product use in real time,and results in more efficient shipping.This automated inventory management system ensures that customers have uninterrupted access to supplies while reducing the effect on our planet.In addition,Promega purchases carbon credits to offset all greenhouse gas emissions from th

214、e Helix program,including energy usage and distribution of units and product stocking.In 2019,Helix on-site stocking offset 650 tons of emissions worldwide by supporting the following projects:Blandin Improved Forest Management Project in Minnesota,United States Rimba Raya Biodiversity Reserve REDD+

215、in IndonesiaHelix carbon offsets support the Blandin Improved Forest Management Project Promega UK Helix Awards go to accounts that reduced impacts from product distribution the most by partnering with Helix.Since 2010,the Helix program has offset nearly 7,000 tons of carbon dioxide,equivalent to th

216、e emissions from 160,000 barrels of oil.To see more information and learn how to participate,please visit: and saved 12,700 kg of dry ice,avoided 32 metric tons of carbon dioxide and eliminated the need for more than 3,000 EPS coolers.We are currently analyzing additional product lines for this tran

217、sition to further reduce carbon emissions and minimize waste.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO40|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Minimizing Effects from Business TravelIn the last year,we saw a 15%reduction in emissions fro

218、m business travel thanks to increased adoption of carbon offsets.Business travel via air,automobile and rail comprise approximately 10%of our current carbon footprint.As we look to the future,we recognize that use of public transit and alternatively fueled vehicles will be key in helping us reduce c

219、arbon emissions while staying connected.In a survey completed last year,fifty-six percent of respondents at our Promega campus said they would consider an electric vehicle(EV)for their next vehicle purchase,and nearly half of respondents said they would be more likely to lease or purchase when Prome

220、ga installs more charging stations.Since that survey,we renovated the parking garage at our Promega campus,significantly expanding our electric vehicle chargers.We are currently able to power 34 vehicles simultaneously and have Promega employee Frank Fan takes advantage of the opportunity to charge

221、his new electric vehicle at work.wired the structure to be able to add additional chargers in the future.Charging stations are also available at Promega Benelux,Promega AG and Promega Biosciences in California.“Workplace electric vehicle charging is very consistent with our corporate culture and sus

222、tainability values.We encourage employees to have that mindset at work and at home.We support employees who choose EVs by having chargers available here for them to use.”DAN MOTLPromega Senior Director of Facilities INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH A

223、DDITIONAL INFO41|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Carbon offsets are another strategy used to mitigate emissions from unavoidable travel.Since 2009 we have offset over 3,000 tons of CO2 from automobile travel in North America through the Emkay GoGreen program.Our North American branch als

224、o elected to offset emissions from air travel with over 550 tons offset in 2019 supporting reforestation efforts in the Amazon.Alternative TransportationAlternative transportation programs have been implemented by a number of locations worldwide to reduce environmental effects.Employees are encourag

225、ed to use public transportation,ridesharing or biking to work.All buildings at Promega Madison and Promega Biosciences in California offer bicycles for employees to use,as well as resources to support cyclists,including access to pumps and bike repair kits.Many locations worldwide have similar progr

226、ams in place.The Promega North American branch offset air travel in 2019 by protecting rainforests in Brazil through the Acre Amazonian Rainforest REDD+Business TravelCarbon FootprintTons of CO2 Per Million USD201520199.19.19.08.79.3 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE

227、 COMMUNITY TOUCH ADDITIONAL INFO42|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Non-Hazardous WasteCubic Meters Per Million USD20152020Goal30.536.635.332.4LandfilledRecycledIncinerated14.232.60.320190.60.40.40.419.314.716.320.120.913.015.215.714.815.2Hazardous WasteKilograms Per Million USD2015Recycl

228、edTreatedIncinerated262.0277.2289.0246.72019284.116.883.8161.415.1101.8160.3105.169.2114.8137.858.949.9162.362.859.0PRESERVING NATURAL CAPITALMinimizing WasteTo reduce waste,Promega locations globally focus on avoiding single-use and difficult-to-recycle materials,enhance recycling programs and incr

229、ease employee awareness of what is recyclable.This has included segregating materials for recycling,composting and encouraging reuse by providing reusable materials in cafeterias and kitchenettes.Employees embrace the mantra“Reduce,Reuse,Recycle”and have championed this effort.In 2019,we saw recycli

230、ng levels increase by 2%and landfilled waste continue to decrease due to the following efforts:The recycling of nitrile gloves and protective garments has been one of our most successful programs to date.In partnership with Kimberly-Clark Professionals Rightcycle Program,we diverted 4.2 metric tons(

231、over 8,500 pounds)of personal protective equipment from landfills in Wisconsin and California.Promega was again recognized with the Chelsea Santucci Greenovation Award in 2019.“Working with the Sustainability Team adds another dimension to my job and highlights an additional way that Promega helps t

232、o create a better world.My experience with sustainability generates value that goes beyond just my interactions at work.”EMMANUELLE KILLIAN-MARTEL Genomic Product Manager,Promega France INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO43|PROMEGA CORPO

233、RATE RESPONSIBILITY REPORT 2020 Promega locations globally have made concerted efforts to reduce plastic consumption by switching to glass cups and other reusable materials instead of plastic.The Promega campus in Wisconsin as well as offices in California,Switzerland,France,Germany and the UK are j

234、ust some of the locations to recently ban single-use materials.When reusable materials are prohibitive we use plant-based and recyclable materials.Segregating plastic shrink wrap,banding and bottles for recycling from our shipping and dispensing areas across the Promega campus allowed us to recycle

235、over 17 tons of plastic in the last year.The Sustainability Committee at our Promega campus held recycling lunch n learns,coordinated removal of plastic cups from watercoolers and piloted bokashi composting to help minimize waste going to landfills from a Sustain Dane Summit hosted at Promega.Facili

236、ties in Madison,WI,and San Luis Obispo,CA,feature employee-managed composting programs to divert organic waste and support our employees passions for gardening.Over 140 employees participated in the annual electronics recycling drive at our Promega Earth Day celebration.The drive set a record by col

237、lecting over 12,481 pounds or 5,661 kg of materials.Managing Hazardous and Infectious WasteIn the biotech industry,manufacturing processes can require use of potentially hazardous substances,along with the obligation to minimize waste and ensure its proper disposal.Promega looks to use vendors that

238、can help us reuse and recycle waste.In kit packaging we are moving away from plastic bags and use divider boxes.This helps to eliminate at least 50 bags per day.Our annual recycling drive for Earth Day collected over 5 tons of material.Water UsageThousands of Liters Per Million USD20152020Goal201934

239、2334307283250291250 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO44|PROMEGA CORPORATE RESPONSIBILITY REPORT 202044|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Conserving WaterIn the last year,gross water usage decreased by over 7.5 million liters

240、or 2 million gallons.Since 2015,water usage has been reduced by 27%as indexed to revenue.Promega evaluates initiatives to conserve water in manufacturing,landscaping and other everyday needs.Notable reductions were seen at the Feynman Center in Madison,WI,as a result of a project to reuse wastewater

241、 generated from our water purification system.This project alone saves over 1 million gallons or 3.7 million liters annually.Many global locations incorporate design features to conserve and ensure proper disposal of water.Offices in Sydney,Australia,collect rainwater for cleaning,flushing toilets a

242、nd irrigating plants.Similarly,the Madison-based global headquarters uses rainwater collection and rain gardens for natural filtration.Promega Biosciences in San Luis Obispo,CA,has a long history of water conservation projects and a custom-designed water recirculating system for distilled water.In t

243、he last ten years,gross water usage has decreased by over 50%at our San Luis Obispo facility despite a significant increase in headcount and manufacturing levels.“Company-wide,around the world,were continually looking for ways to reduce the environmental impacts of everything we do.Every improvement

244、 is shared,celebrated,and motivates us to keep looking for better ways of doing things.”GHISLAINE SAMWAYS,General Manager,Promega Australia INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO45|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Reducing Packag

245、ing MaterialsMany Promega products are temperature-sensitive,creating unique requirements in packaging that involve use of dry ice,gel ice and foam coolers.We continually evaluate the effect of packaging on the environment,and search for innovative ways to reduce packaging,use environmentally friend

246、ly materials,and design for recycling or reuse.Environmental sustainability,product protection and quality are all key priorities.The new Promega kit packaging design was chosen as a winner in the 2019 Graphic Design USA Package Design Award in the Sustainable Packaging Category.Promega has implemen

247、ted new kit packaging boxes that use sustainably sourced materials,reduce material used,and promote recycling for customers.Last year,Promega was recognized with the Graphic Design USA Award for Sustainable Packaging for these new kit boxes.To reduce the environmental effects of packaging,Promega ha

248、s also:Switched to smaller shipping boxes to use less packaging materials.Incorporated new materials that provide better insulation and reduce the amount of dry ice needed.Implemented self-adhesive shipping boxes at our European logistics hub in Waldorf,Germany,that will avoid over 2,800 meters of t

249、ape each year.Implemented packaging designs that minimize air space while also reducing dry ice usage and shipment weight.Changed to unbleached shipping boxes that contain sustainably harvested materials.Promega is supporting and reporting progress toward the Australian Packaging Covenant Organizati

250、ons goal of preventing packaging materials from ending up in the landfill by 2025.46|PROMEGA CORPORATE RESPONSIBILITY REPORT 2019 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO46|PROMEGA CORPORATE RESPONSIBILITY REPORT 202046|PROMEGA CORPORATE RESP

251、ONSIBILITY REPORT 2020People CareEmployees celebrate the opening of the new Promega UK facility in 2019.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO47|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020People CarePromega provides the opportunity and spa

252、ce for employees to grow as individuals and professionals.Our culture nurtures creativity,prioritizes emotional and physical well-being,and emphasizes self-actualization.Employees are given flexibility in how they work,and we acknowledge the individual differences of each employee.Our 19 worldwide l

253、ocations provide support in ways that meet the specific needs of each region and encourage employees to achieve a balance of work-home integration.We live the notion that every one of our employees has the potential to make a meaningful difference.And they do.Promega is so much more than a place to

254、work.It is a family where we all support each other to be our best selves.We are blessed with a culture of giving and going the extra mile just because its the right thing to do.Promega provides the opportunity to create a different way of working and being.DARBIE MILLERDirector,HR Organizational De

255、velopment47|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO48|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020NURTURING EMPLOYEE CREATIVITY,GROWTH AND SELF-ACTUALIZATIONFeeling fulfilled is crucial to our dev

256、elopment as humans,and realizing our personal potential means we grow and strive to achieve our true capabilities.As a company,Promega provides a work environment and culture that offers each employee the opportunity for individual development and to build meaningful relationships with one another.T

257、he Promega Culture The psychology of the organizationour“cultural DNA”provides a foundation through which company principles and operations are shaped.For us,these principles include:1.Nurturing creativity,self-discovery and individual growth,creating an environment where the unique contributions of

258、 each employee are embraced.2.Believing that both people and companies can self-actualize,and that growth at either level lifts the other into realizing their greater potential.3.Structuring a culture that reinforces the idea that all stakeholders(customers,employees,community and shareholders)can f

259、ind growth and transformation through:a.Organizational reporting that provides for easy collaborative communication across and at all levels of the organization.b.Decision-making that is shared among the group,not controlled,and the organization remains nimble because people in key nodes are empower

260、ed to act,having considered all voices.c.Physical work environments,including design,lighting,communication systems and access to information.The team at the Promega Europe Training and Application Lab(PETAL)enjoys some bowling.Promega employees in the field.INTRODUCTION CORPORATE MIND PRODUCT REACH

261、 PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO49|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 d.Resources that employees need to do their best work.e.A financial structure that supports organizational goals and values for personal development.Economic metrics provide guidance on sustainab

262、le business practices but are not the only drivers for business decisions.f.Selection and support of employees entering the organization who reflect our values.4.Contributing to life science research and related discoveries have been and will continue to be important to society and human development

263、 by designing and supplying products,systems and services that simplify this research and give more reliable and accurate results.We seek employee feedback in annual climate surveys and monthly employee sessions to understand employee happiness and engagement.Feedback from the survey in 2018 highlig

264、hted that employees feel they work in a collaborative environment,are proud to work at Promega,enjoy the people they work with,and find their work to be meaningful.2019 Climate Survey Top Ten QuestionPositive I work with great people.99%Im proud to work for Promega.98%I have a reasonable work schedu

265、le.97%Promega has an overall good reputation in the community.96%I have the tools and resources to do my job.96%I have an intimidation-free and harassment-free workplace.96%I work in a collaborative environment.95%Id recommend Promega to my friends.95%My manager is approachable.94%I have a boss with

266、 high integrity.94%Promega BioSystems in Korea visited Jeju Island to celebrate its anniversary and the production of over 500 Maxwell Instruments last year.Teams stayed active by surfing,paddle boarding,fishing and horseback riding.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE

267、COMMUNITY TOUCH ADDITIONAL INFO50|PROMEGA CORPORATE RESPONSIBILITY REPORT 202050|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Creating Workspaces to InspireAs a business based on creative output and employee satisfaction,Promega prioritizes environmental quality and stimulating experiences in the wor

268、kplace.Invigorating spaces come both in the design and variety of space offerings.Key components of workspaces include abundant light(natural light whenever possible),a variety of art and comfortable,warm furniture.The variety of spaces gives employees the opportunity to work in a creative“third spa

269、ce,”exercise,meditate or grab a bite to eat.Throughout Promega,there are opportunities to discover stories,history and whimsy.Employees are engaged in the design of new space and the renovation of existing workspaces to improve functionality,ergonomics and foster group collaboration.This process con

270、siders all aspects of a space,including types and quality of lighting,sound levels and air flow.Additionally,customizable workspaces for employees encourage collaboration.Architecture and design that“brings the outdoors in”encourages an appreciation of natural beauty.For example,our new facility in

271、Germany incorporates an extensive array of indoor plants and trees to add life and warmth.Locations globally use local resources,art and culture to provide comfortable,functional and unique work environments.Our priority is to create environments with an attention to detail that is inspiring,flexibl

272、e and aligned with the needs of employees.Our priority is to create environments with an attention to detail that is inspiring,flexible and aligned with the needs of employees.Creative workspaces invigorate and inspire employees.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMM

273、UNITY TOUCH ADDITIONAL INFO51|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Cultivating Emotional and Social Intelligence(ESI)To foster a supportive and dynamic work environment,Promega embraces the principles of emotional and social intelligence(ESI).ESI helps employees improve relationships,manage s

274、tress and enhance connections.The components of the ESI program include 1:1 and group coaching,daily guided meditations,formal trainings and company-wide initiatives.Beyond strengthening our ESI skills,these programs bring employees together in ways that are both professional and personal,thereby st

275、rengthening our community.To date,over 200 employees have attended our flagship program,the ESI Bootcamp.The ESI Bootcamp is an immersive experience that gives participants the time,space and support to focus deeply on learning and integrating the building blocks of ESI.As the number of employees ac

276、tively participating in ESI activities grows,we have continued to expand and deepen our programs with the fundamental goals of seeding and anchoring ESI widely throughout the business.A first cohort of Promega employees has now engaged in a job enrichment,train-the-trainer program called the Advance

277、d Practitioner Training(APT),which makes ESI a formal part of the APT graduates role.Through dedicated Communities of Practice,these employees refine and share best practices and come to serve as listeners and advisors to each other on journeys of personal and professional growth.We have also engage

278、d Promega employees to act as ESI Teaching Assistants who are first tasked with deepening their own understanding of the topics they will teach.In so doing,their ESI Building Blocks courses come alive with personal stories,making ESI more real and tangible to fellow employees.People from all walks o

279、f Promega life report that our shared ESI language allows us to connect and evolve in response to challenges in ways that are more satisfying and effective.“I am participating in the most rewarding and exciting project of my careerembedding Emotional and Social Intelligence(ESI)deeply and broadly th

280、roughout Promega.The tremendous leadership support;the unparalleled enthusiasm of the entire Promega team;and the capacity of an open and resilient organization to learn and integrate new ideas quickly,yet still with heart,has produced a culture that can stand as a role model for businesses everywhe

281、re.”Tim Weitzel ESI ArchitectPromega KK actions to support employees on their ESI journey included scratch art cards and body scan meditations.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO52|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020PROVIDING PE

282、RSONAL DEVELOPMENT AND GROWTH FOR EMPLOYEESPromega takes an innovative approach to employee development that focuses on a series of conversations to recognize employee strengths and encourage growth based on employee passions.Since growth starts from the inside,we have shifted from the more standard

283、 manager-driven review process to one that starts with the employee.More and more departments use a conversational approach that facilitates individual development plans,personalized growth goals and a listening session to understand what our talent needs to keep them with Promega.Leadership Trainin

284、g and Employee DevelopmentProfessional development programs like Coaching for Leaders,Leadership Forum,Transformational Leadership,Leadership Conversations and Manager Roundtable programs support managers at all levels.Individually targeted leadership development is available on site,or with externa

285、l or training partners.In addition,organizational development services include talent management resources,personality and leadership assessments,coaching and consulting.Initially these programs were limited to North America,but they have expanded to our branches in Italy,Sweden,France,BNL,Spain and

286、 UK in the last year.Employee development sessions are available for all employees and currently include Seeking&Receiving Feedback,Influencing without Authority,Conflict Management and much more.Due to overwhelming popularity,the number and diversity of programs increased in the last year.Two sessi

287、ons on Coaching for Individual Contributors were added Employees at Promega KK in Toyko connect and cultivate their emotional and social intelligence skills.The team at Promega Biotech Ibrica in Spain take part in leadership training.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE

288、 COMMUNITY TOUCH ADDITIONAL INFO53|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020“I am so grateful for this mind-bending experience.I made“To Do”notes to myself during the progression of the day-long event,and followed through with expanded attitudes and directed actions,built upon the courses concept

289、s.I feel Ive been changed for the better in many wonderful ways.”KATHARINE HOFFMAN Senior Scientist in Response to Coaching for Individual Contributorsin 2019 for 45 attendees and 75 people on the wait-list before the 2020 sessions were even advertised.These on-site programs are facilitated by Human

290、 Resources team members or external training partners.Scientific TrainingThe Scientific Training team designs,develops and implements product and sales trainings for employees around the globe,which are delivered in live and virtual classrooms.Live courses are available in Madison,WI;Lyon,France;and

291、 Singapore to address the training needs of employees globally.These facilities also incorporate video conferencing equipment for scientists and trainers to participate from off-site locations.English Classes for EmployeesOur branches in Korea,Japan,and Germany offer employees English lessons to imp

292、rove communication across the company and with clientele.These efforts help employees access the resources they need to advance their career.Employees have added a sticker with the Principles of ESI to the back of their badge to help remind them to check in with yourself and listen with empathy thro

293、ughout the day.Training at PETAL(Promega European Training and Application Laboratory)in Lyon,France.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO54|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Employees across Promega let loose to The Git Up Chall

294、enge in 2019.Promega AG from Switzerland visited the Aletsch Glacier,the largest glacier in the Alps,on a company outing in August 2019.Our Japanese team on a trip to Hokkaido to build connections with their colleagues and appreciate the natural beauty of the region.Managers at Promega Biotec Ibrica

295、 participated in the DISC personality assessment training program to facilitate the communication process between different departments.Employees at Promega headquarters who are musically inclined have joined forces to create the band“Lead Generation.”For over a decade,employees ranging from scienti

296、sts,marketers,IT specialists,and administrators have come together to share their talents.Promega Korea celebrated their 10th anniversary by visiting Namsan Hanok Village or “A Village of Traditional Houses in the Namsan Valley”to appreciate Korean history and reflect on their successes.Colleagues a

297、t Promega France play bocce ball on the courts outside their office.Promega Australia celebrating their 35th Anniversary on the water in Sydney.Promega Italia celebrating their move to a new office space in 2019.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDIT

298、IONAL INFO55|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020BUILDING RELATIONSHIPS AND CONNECTIONSWe cultivate an environment of connection among employees so strong bonds can be nurtured and extend through the company to our families and community.From team-building activities to employees joining tog

299、ether to share in hobbies,strong relationships are the foundation of what we do.Eppendorf Exchange ProgramFor Promegas 40th anniversary,we received a generous gift from a friend in the industry:Eppendorf.The teenage child of any Promega employee was given the opportunity to visit an Eppendorf family

300、 in another country,and in return host the Eppendorf familys child in their home.The goal was for both children to experience another culture and build a relationship with each other.In 2019,11 Promega children bid good-bye to their parents,hopped on a plane,and flew to Germany.There they would stay

301、 for three weeks or more with a family theyd never met.For all involved,it proved to be a valuable and positive learning opportunity.“The change in the way I view the world,a more artistic and abstract view,will serve me well in school and life as I move forward.Before I took this trip,I was told th

302、at it would change my life.I never realized how true that would be.”EPPENDORF EXCHANGE PARTICIPANTTeenage children of Promega and Eppendorf employees spent the summer of 2019 experiencing each others countries and cultures.250+WELLNESS FAIR ATTENDEES20FITNESS CLASSES/WEEK142ACUPUNCTUREAPPOINTMENTS53

303、0FLU VACCINES ADMINISTERED768NUTRITIONAL AND MENTALHEALTH COUNSELINGSESSIONS ADDED IN 2019381FUN RUNREGISTRANTS1,600WELLNESS CENTER VISITS290EMPLOYEE MASSAGESAT THE ZEN ZONE774KNOW YOUR NUMBERSPARTICIPANTS4NEW YOGA INSTRUCTORSADDED IN 2018 WITH A TOTAL OF8YOGISPHYSICAL THERAPY APPOINTMENTS1,674PROME

304、GA WELLNESS BY THE NUMBERS:2019 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO56|PROMEGA CORPORATE RESPONSIBILITY REPORT 202056|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNIT

305、Y TOUCH ADDITIONAL INFO57|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Biopathways A new event,called Biopathways,was offered for junior-high and high school children of Promega employees in 2019.This was our take on“Bring your child to work day,”allowing children the chance to learn about their pare

306、nts company and expose them to the multitude of careers revolving around science.We want the future generation to be excited about what they can do in this industry and give them insights that can proactively help them turn an“undecided”degree into something they are sure of.PRIORITIZING EMPLOYEE HE

307、ALTH AND WELL-BEINGPromega takes a multifaceted approach toward employee well-being.Physical health and wellness start with safety but expand to include fitness and health care facilities,wellness programs and benefits packages.Employee SafetyEmployee health and safety is a high priority.Environment

308、al Health and Safety programs are committed to establishing,maintaining and improving work environments for the safety and well-being of our employees as well as the communities in which we operate.Resources and Benefits That Support Employee Wellness Promega employees are offered comprehensive bene

309、fit packages based on country standards.These programs typically include medical,dental and vision coverage as well as a competitive 401(k)plan and flexible spending accounts for health care.Short-and long-term disability insurance,life insurance,tuition assistance and paid time off are also provide

310、d to ensure the well-being of our employees and their families.“Emmy has been instrumental in helping me transform my life and get healthy.I started working with her last February She recommended a new diet for me,helped educate me on what to eat,what to avoid,and how to balance it.And,she helped mo

311、tivate me to start exercising regularly,and the right way.Since working with her Ive lost 30 pounds and have gotten my bio numbers back on track.Her expertise,along with Promegas great workout facilities,have given me the opportunity and motivation to get healthy.”Michael Bjerke,Sr.Product Manager,P

312、romega INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO58|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Encouraging Active LifestylesA multitude of options are made available to employees so that they may develop healthy and active lifestyles supported

313、 by Promega at our headquarters and across the globe.Many locations offer on-site fitness facilities,yoga classes and group fitness instruction.Some branches also offer reimbursement for health club memberships and support for participation in sports or competitive events like marathons or triathlon

314、s.Promega C25kEach year Promega challenges employees to train for the annual Couch to 5k program,which provides new runners the education and training support to complete a 5k race.Wellness Center OfferingsThe Wellness Center located at our Madison,WI,headquarters provides all employees on-site heal

315、th consultations and counseling,which is available five days a week.Services include routine blood draws,travel and routine immunizations,consultations for general health concerns,physical examinations and physical therapy.In 2019,Promega added a licensed professional counselor and a registered diet

316、ician to the Wellness Center Staff,offering free consultations to all employees.Counseling services can help a variety of needs like anxiety,depression,nutrition or navigating career and workplace challenges.Health Assessments with Know Your NumbersEach year Promega employees are encouraged to parti

317、cipate in the Know Your Numbers program,which provides a free basic health screening for those interested in participating.Employees obtain a finger-stick test and meet with our Nurse Practitioner the same day to review their results.This program is offered every year and aims to help employees unde

318、rstand what health risks they might face.These diagnostic indicators can help employees formulate a plan around lifestyle changes they can make to prevent or delay the onset of certain diseases such as diabetes and heart disease.In 2019,774 employees participated in this program.Supporting Employees

319、 During Times of NeedCaregiver Leave was made available to Promega employees in the US for the last few years.Employees can use two weeks of paid time to care for aging parents,ill spouses,children with medical needs,or time off to bond with a newborn or newly adopted child without sacrificing their

320、 own paid sick leave or vacation.Nearly two hundred employees have used this program since it was offered.“I am grateful to work for Promega because the way of thinking is different,and my experiences have made me a stronger,more relaxed and empathic person.”NICOLAS SCHAFER Clerk Export&Spoke Suppor

321、t,Promega Euro HubPromega received a Health Transformation Award from The Alliance in recognition of our Caregiver Leave as a progressive benefit offering in 2019.INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO59|PROMEGA CORPORATE RESPONSIBILITY REP

322、ORT 20207Promega Annual Fun Run/Walk 5kThe 10th Annual Promega 5k Fun Run/Walk encourages employees to stay active and collects donations for the local food bank.In 2019,the team collected 565 pounds in addition to monetary donations.Eating Well,Living WellEmployees have access to fresh and local pr

323、oduce from our on-site culinary garden at the Madison,WI,location.Thousands of pounds of produce are harvested annually from the garden and,in conjunction with over three dozen local farms,are used to create healthy and organic menus across the campus.Employees may also select their own plots within

324、 an on-site community garden so they can exercise their own green thumbs.An additional way Promega supports employees is with take-home meals provided by the culinary team at Promega.1.Employees at Promega Biosciences in California played dodgeball as part of a fundraiser for Big Brothers and Big Si

325、sters.2.Employees from Promega Shanghai took part in a cycling event to encourage employees to bike more.Seven employees participated with three in the team competition group winning third place.3.Employees at Promega Biotech Ibrica participate in sporting events like Carrera Internacional de la Cie

326、ncia to support the scientific community and stay active.4.The culinary team at Promega uses fresh and local produce from the culinary garden and local farms to create healthy and organic menus.5.Employees from Promega Italia participated in Wanderlust,dubbed the worlds only mindful triathlon featur

327、ing a 5k run,75 minutes of yoga and a 25-minute guided meditation in an outdoor setting.This gathering looks to spread love,peace,and compassion.6.Employees at Promega Singapore participate in the Annual Fun Run.7.The team at Promega India participated in Airtel Delhi Half Marathon to stay active an

328、d help raise funds for charitable work in India.Over 40,000 people participated and raised the equivalent of 65 million USD.8.Our team at Promega France has added honeybee hives at their office in Lyon to help safeguard the bee population and educate employees on how to maintain a hive.An added bene

329、fit has been the ability to harvest fresh honey for employees.1352468Community Touch INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFOPromega was a Gold Sponsor for the Wisconsin Science Festival interacting with thousands of children on school field

330、trips about the science of bioluminescence.60|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020 INTRODUCTION CORPORATE MIND PRODUCT REACH PLANET AWARE PEOPLE CARE COMMUNITY TOUCH ADDITIONAL INFO61|PROMEGA CORPORATE RESPONSIBILITY REPORT 2020Community TouchIn communities across the globe,Promega employees

331、 find meaningful ways to make a difference.They connect directly with their local communities to identify volunteer and philanthropic opportunities,empowering them to work with organizations they care about.After all,they are most familiar with the unique needs of their own communities and the most

332、effective approaches to address those needs.They seek to better the world in the distinctive ways that match their unique skills and bring meaning to their lives.Promega celebrates this passion and supports a culture that catalyzes employee involvement through policies such as volunteer time-off and

333、 matching gifts.I am amazed by the open hearts of the people at Promega.They have a genuine desire to make a difference in communities around the world by educating and inspiring young minds,volunteering their time,and donating to causes they are passionate about.There is an innate awareness that we all rise by lifting others up.STEPHANIE SHEAEmployee Giving Coordinator61|PROMEGA CORPORATE RESPONS