全國豬繁殖與呼吸綜合征流行情況、其影響因素及對生產成績的影響李超斯, 勃林格殷格翰.pdf

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1、2022年全國豬繁殖與呼吸綜合征病毒普查數據，對生產成績的影響及風險因素Prevalence,economic loss,and risk factors of porcine reproductive and respiratory syndrome in China in 2022報告人:Speaker勃林格殷格翰豬市場部豬藍耳病&豬瘟技術 Boehringer Ingelheim animal health Associate Technical&SPC Manager李超斯 獸醫學博士 Dr.Chaosi Li數據引自“百場計劃”項目 data cited from“Century P

2、roject”豬繁殖與呼吸綜合征以下簡稱“藍耳病或PRRS”porcine reproductive and respiratory syndrome is abbreviated to PRRS in the following content 1.研究背景及目的Research background and objectives 2.2021Q4-2022Q4全國PRRSV普查數據The prevalence of PRRSV in China from Q4 2021 to Q4 20223.PRRSV陽性不穩定(I)對生產成績的影響 PRRSV positive unstable(I)

3、impact on abortions and weaned piglets compared with PRRSV stable(II)farms4.影響PRRSV多樣性及影響PRRSV陽性不穩定(I)的因素分析Analysis of factors that impact on genetic diversity of PRRSV and farm positive unstable(I)5.總結及致謝 Take home message&Acknowledgement 主要內容主要內容 Topics數據引自“百場計劃”項目 data cited from“Century Project”

4、豬繁殖與呼吸綜合征以下簡稱“藍耳病或PRRS”PRRS stands for porcine reproductive and respiratory syndrome in the following slides 研究背景研究背景 Background非洲豬瘟后生產成本普遍上升，生產成績降低 After 2019,Production cost raise while performance slump PRRSV或是拉高生產成本，降低生產成績的原因之一 PRRSV is likely as one of the root causes of low cost-benefit perfor

5、mance2022年國內PRRSV流行情況，野毒核酸轉陽階段分布情況？What was the prevalence of PRRSV in China in 2022,and the distribution of field PRRSV infection stages?2022年國內PRRSV主要影響哪些生產成績？具體影響多少？How performance negatively influenced by PRRSV?To which extent?導致PRRSV陽性不穩定(I)和場內毒株多樣性增加的主要因素有哪些？What are the main factors leading t

6、o PRRSV positive unstable(I)and increased diversity of virus strains within a farm?2021年養殖成本-博亞和訊Boyar(2021 rearing cost)自繁自養：17.5元/千克￥/kgSelf-breeding外購育肥 W2F：25.0元/千克￥/kg Purchasing for feeding W2F嘉吉分析（2021年4月份養殖成本）Cargill(April 2021 rearing cost)自繁自養：17.0元/千克￥/kgSelf-breeding外購育肥W2F：27.5元/千克￥/kgP

7、urchasing for feeding W2F出生活仔率：90.53%Live birth:90.53%1.08%出生活仔率：91.61%Live birth:91.61%0.95%斷奶前死亡率：12.15%Pre-wean mortality:12.15%斷奶前死亡率：11.20%Pre-wean mortality:11.20%25.22周斷奶仔豬/千頭：507.74Weekly weaned piglets/1000 sows:507.74周斷奶仔豬/千頭：532.95Weekly weaned piglets/1000 sows:532.958.26%斷奶到出欄死亡率：13.04%

8、W2M mortality:13.04%斷奶到出欄死亡率：4.78%W2M mortality:4.78%2.4%出欄時體重不達標比例：17.9%Unmet target at slaughtering:17.9%出欄時體重不達標比例：15.5%Unmet target at slaugthering:15.5%1.Torrents D,Miranda J,Gauger PC,Ramirez A,Linhares D.Effect of PRRSV stability on productive parameters in breeding herds of a swine large int

9、egrated group in Spain.Porcine Health Manag.2021 Feb 26;7(1):21.doi:10.1186/s40813-021-00203-4.PMID:33637120;PMCID:PMC7908702.2.Moura CAA,Philips R,Silva GS,Ramirez A,Gauger PC,Holtkamp DJ,Linhares DCL.Association of wild-type PRRSV detection patterns with mortality of MLV-vaccinated growing pig gro

10、ups.Prev Vet Med.2021 Apr;189:105270.doi:10.1016/j.prevetmed.2021.105270.Epub 2021 Jan 27.PMID:33550121.3.L.Linhares.et.al,Breed-to-finish risk associated with increased proportion of lightweight pigs marketed,2022,53rd annual meeting of the AASV陽性不穩定（陽性不穩定（I）Positive unstable(I)陽性穩定（陽性穩定（II）Positiv

11、e stable（II）研究背景-PRRSV拖累行業生產水平Background:PRRSV is a burden of industry production performance豬群數量Number of herds損失金額陽性穩定（陽性穩定（I）Positive Stable(I)不穩定（不穩定（II）Unstable(II)Trevisi P,Amatucci L,Ruggeri R,Romanelli C,Sandri G,Luise D,Canali M,Bosi P.Pattern of Antibiotic Consumption in Two Italian Produc

12、tion Chains Differing by the Endemic Status for Porcine Reproductive and Respiratory Syndrome.Front Vet Sci.2022 Mar 28;9:840716.doi:10.3389/fvets.2022.840716.PMID:35419448;PMCID:PMC8996257.研究背景-PRRSV增加用藥及飼料成本Background:PRRSV imposed medication and rearing costs 治療費用 歐元/公斤保育階段育肥階段陽性穩定（陽性穩定（I）Positiv

13、e Stable(I)不穩定（不穩定（II）Unstable(II)飼料轉換率研究目的 Objectives收集PRRSV全國流行大數據，為行業提供數據參考和決策支持 Integration of PRRSV epidemiological data providing support to the industry for reference and decision making量化2022年國內PRRSV對生產成績的影響數字 Quantification of the impact of PRRSV on production performance in 2022造成PRRSV陽性不穩

14、定（I）的主要因素及多樣性的原因 Analysis of main causes of PRRSV diversity and positive unstable(I)通過大數據的積累，為行業提供PRRS防控建議及數據支持，助力行業成長 Through data compilation,providing suggestions on PRRS prevention and control and data support to the industry黑龍江:23遼寧:19河南:6京津冀:17福建:44云南:32廣東:42廣西:16江西:34川渝:59浙江:30山東:32湖北:12江蘇:1山

15、西:10安徽:0湖南:9貴州:12甘肅:3陜西:18內蒙古:4吉林:10青海:0新疆:8西藏:0海南:0臺灣:0寧夏:0研究方法：項目場分布于全國23個省市及自治區Research methodology:the study covered sites distributed in 23 provinces,cities,and autonomous regions across China豬場分布：截止2022年12月共計437個場次，覆蓋50萬頭母豬，豬場規模在500-6000頭經產母豬存欄Distribution of swine farms:500K sow inventory wit

16、hin 437 farm counts in total with a scale of 500-6000 sows inventory as of Q4,2022.數據引自“百場計劃”項目 data cited from“Century Project”豬繁殖與呼吸綜合征以下簡稱“藍耳病或PRRS”porcine reproductive and respiratory syndrome is abbreviated to PRRS in the following content 主要內容主要內容 Topics1.研究背景及目的Research background and objecti

17、ve 2.2021Q4-2022Q4全國PRRSV普查數據The prevalent evolution of PRRSV in China from Q4 2021 to Q4 20223.PRRSV陽性不穩定(I)對生產成績的影響 PRRSV positive unstable(I)impact on abortions and weaned piglets compared with PRRSV stable(II)farms4.影響PRRSV多樣性及影響PRRSV陽性不穩定(I)的因素分析The factors impact on genetic diversity of PRRSV

18、and farm positive unstable(I)5.總結及致謝 Take home message&Acknowledgement 2021Q4-2022Q4 總反應數及野毒檢出率#and reaction rate of PRRSV in China from Q4 2021 to Q4 2022178024167518總反應數#of total reactions陽性反應數#of PCR positive reactions野毒陽性反應數#of wild PRRSV positive reactions24%32%2.1 樣本檢出率:野毒抗原陽性反應數/總反應數Sample-sp

19、ecific detection rate:number of positive reactions/total number of reactions 25%33%23%19%17%反應數#of PCR reactions野毒樣本檢出率%of wild PRRSV positive reactions15251368156521968642022Q42021Q42022Q12022Q22022Q3注：野毒包括非疫苗毒株及測序失敗樣本Note:Wild viruses include non-vaccine strains and failed sequencing samples三種樣本的野

20、毒反應數及檢出率%of PCR positive reactions for three phases of piglet herds 64810022628斷奶階段仔豬血Weaning serum38%25%510572300117%19%睪丸處理液PF62284218898-10周齡口水液Oral fluid 45%33%隨仔豬日齡增長，陽性檢出率逐漸升高 With the age of piglets increased the PCR detection rate increased保育期野毒樣本檢出率明顯上升（8%）除難以避免的窩內水平傳播，或還存在一定的窩間傳播 The filed

21、 PRRSV detection rate increased by 8%from PF to Weaning serum verified that horizontal transmission were existed in farrowing rooms 睪丸處理液陽性樣本中89%為野毒陽性；證明大多數早期感染為場內野毒株所引起 89%positive reactions in PF are field PRRSV2.2 野毒樣本檢出率:睪丸處理液為17%；8-10周齡仔豬為33%Samples PRRS field virus positive reaction rate are 1

22、7%and 33%for processing fluid and 8-10-weeks-old oral fluid respectively 總反應數#of total reactions陽性反應數#of PCR positive reactions野毒陽性反應數#of wild PRRSV positive reactions注：野毒包括非疫苗毒株及測序失敗樣本Note:Wild viruses include non-vaccine strains and failed sequencing samples總反應數#of total reactions陽性反應數#of PCR posi

23、tive reactions野毒陽性反應數#of wild PRRSV positive reactions總反應數#of total reactions陽性反應數#of PCR positive reactions野毒陽性反應數#of wild positive reactions總場次數，陽性場數，野毒陽性場數#of farm in total,positive farms and field PRRSV positive farms25431343758%72%總場次數#of total farms陽性場次數#of PCR positive farms野毒陽性場次數#of wild PR

24、RSV positive farms野毒陽性場次254個，占比58%，Field PRRSV positive farms rate were 58%五大防控區中，僅有西南區的野毒場檢出率低于總檢出率 Southwestern was the solo district below the average value區域劃分參考農業農村部2021年印發非洲豬瘟等重大動物疫病分區防控工作方案（試行）文件836926114145514022558661%58%85%48%59%北部區Northern東部區(Eastern)西北區(Northwest)西南區(Southwest)中南區(Centra

25、l-South)總場次數(#of farms)野毒場次數（#of Positive farms)野毒場檢出率(Field PRRSV Positive rate)x58%五大防區野毒場檢出率%of field PRRSV positive farms distributed in five preventive districts 2.3 場檢出率：本類別樣本野毒陽性場數/對應樣本送檢場次數Detection reaction by farm:number of farms with samples positive/corresponding sampling farms 31%37%46%

26、58%411412307場次數#of farms 野毒場檢出率%of wild PRRSV farms437斷奶仔豬血Weaning serum8-10周齡仔豬8-10 weeks-old piglets oral fluid三種樣本的野毒場檢出率%of positive farms by three kinds of samples 注：總計為本場送檢樣本中，有一種為野毒陽性，歸類為野毒檢出場三種樣本的場檢出率均高于野毒樣本檢出率（24%），說明國內大部分豬場為野毒陽性，但陽性豬群內占比相對較低From positive detection rate of samples and farms

27、 verified most virus positive farms with small parts of filed PRRSV infection piglets2.4 不同階段豬只野毒場檢出率%of positive farms categized by individual piglet phases 睪丸處理液Processing fluid總計 in total 47%46%4%3%2071991714其它PRRSV-2PRRSV-1PRRSV-1&PRRSV-247%24%14%4%4%3%3%20710359171614128其它（Others）Lineage 1疫苗株（V

28、accine-like)PRRSV-1Lineage 8PRRSV-1&PRRSV-2Lineage 3PRRSV-2多毒株感染PRRS2多毒株流行：項目場當月送檢的所有樣本中包含多種PRRS毒株Multiple PRRS-2 isolates co-circulation:more than 2 isolates were found within 15 months surveillance 2.5 主要流行毒株場檢出數/率Mainly prevalent PRRSV isolates distributed by farms from 2021Q4 to 2022Q4Multiple P

29、RRS-2 isolates co-circulation 2.6 野毒轉陽時間點分布Field PRRSV PCR Conversion phase distribution 注：僅統計次提交樣本類型包含相鄰兩種樣本及以上場次Farms that simultaneously collect all of the three kinds of samples were taken into count and statistics 12867224649%25%8%17%在符合要求的263個場次當中，263 Eligible farms were taken into count and s

30、tatistics 128個存在早期感染（3-5日齡仔豬），占比49%49%of farms were early-infected in 3-5 days old74%場次在斷奶前野毒轉陽 74%of farms PCR conversion before weaning 僅有17%場次在保育末期仍保持野毒抗原陰性 Only 17%farms keep PCR negative before finish#of Farms in analysisPF of 3-5 day-old piglets Weaning serum OF of 8-10 week-old piglets PRC ne

31、gative before finish 主要內容主要內容 Topics1.研究背景及目的Research background and objective 2.2021Q4-2022Q4全國PRRSV普查數據The prevalent evolution of PRRSV in China from Q4 2021 to Q4 20223.PRRSV陽性不穩定(I)對生產成績的影響 PRRSV positive unstable(I)impact on abortions and weaned piglets compared with PRRSV stable(II)farms4.影響PR

32、RSV多樣性及影響PRRSV陽性不穩定(I)的因素分析The factors impact on genetic diversity of PRRSV and farm positive unstable(I)5.總結及致謝 Take home message&Acknowledgement 千頭母豬月流產數:月流產母豬數/當月月末妊娠母豬數*1000Number of monthly abortions per thousand sows:Monthly number of abortions sows/number of pregnant sows at the month end*100

33、0數據統計及分析使用GraphPad Prism 9.3GraphPad Prism 9.3 for statistics and analysis*p0.05;*p0.01;*p0.0013.1 陽性穩定(I)場月千頭母豬流產數少6.4頭The number of monthly abortions per thousand sows is 6.4 less in PRRS stable farms than PRRS unstable(I)陽性穩定（II）場Positive stable(II)x=1.5*x=7.9月流產數/千頭母豬Monthly abortions/1000 sows月

34、流產數/千頭母豬Monthly abortions/1000 sows場1Farm 1場2Farm 2場3Farm 3場4Farm 4場5Farm 5場6Farm 6場7Farm 7場8Farm 8陽性不穩定（I）場Positive unstable(I)陽性穩定（II）場Positive stable(II)陽性不穩定（I）場Positive unstable(I)3.2 本研究中，不穩定與穩定對窩均健仔數無顯著差異No significant difference in the number of alive piglets per litter between PRRS unstable

35、 and stable in the studyNS窩均健仔數:月出生健仔數/月分娩母豬數Number of health piglets per litter:monthly births of health piglets/monthly number of delivering sows數據統計及分析使用GraphPad Prism 9.3GraphPad Prism 9.3 for statistics and analysisNS:無統計學意義NS:Not statistically significantx=10.8x=10.4窩均健仔數Number of health pigle

36、ts per litter 場1Farm 1場2Farm 2場3Farm 3場4Farm 4場5Farm 5場6Farm 6場7Farm 7場8Farm 8窩均健仔數Number of health piglets per litter 陽性穩定（II）場Positive stable(II)陽性不穩定（I）場Positive unstable(I)陽性穩定（II）場Positive stable(II)陽性不穩定（I）場Positive unstable(I)3.3 陽性穩定（II）場，窩均斷奶數多1.6頭The number of weaned piglets per litter is

37、1.6 heads more in PRRS-stable farm*x=10.1x=8.5窩均斷奶數:月斷奶數/上月分娩母豬數The number of weaning piglets per litter:monthly weaning piglets/the number of delivering sows in the preceding month數據統計及分析使用GraphPad Prism 9.3GraphPad Prism 9.3 for statistics and analysis*p0.05;*p0.01;*p0.001窩均斷奶數Weaned piglets per l

38、itter陽性穩定（II）場Positive stable(II)陽性不穩定（I）場Positive unstable(I)3.4 陽性不穩定（I）場母豬場平均月損失17.4萬元/千頭母豬PRRS unstable result in￥174 K losses per month in a 1000 inventory F2W farm 1000頭經產母豬場月經濟損失計算 Ecomic calulation on PRRS unstable（I）F2W farm 1.母豬經濟損失計算（￥/月）Part 1：Losses in Sow herd穩定 PRRS stable不穩定 PRRS uns

39、table母豬流產數#of aborts 1.5 7.9 平均流產時妊娠天數 Average abortion days 85.0 85.0 當月總非生產天數 Total Non-productive days 127.5 671.5 非生產天數成本（￥/日）NPD cost(￥/day）25.7 25.7 流產成本支出（￥/月）Total lost(￥）3,276.8 17,257.6 經濟損失（￥/月）Ecnomic lost from PRRS unstable versus stable (￥)13,980.8 2.斷奶豬經濟損失計算 Part2：Loss for Weaned pig

40、lets基礎母豬數#of sows 1,000.0 1,000.0 當月斷奶窩數 Weaned litters/month 200.0 200.0 窩均斷奶數#of weaned piglets/litter 10.1 8.5 當月總斷奶仔豬數 Total weaned piglets/month 2,020.0 1,700.0 仔豬價格（￥/頭）price per weaned piglets(￥）500.0 500.0 總仔豬售價（￥）Total sells value/month 1,010,000.0 850,000.0 經濟損失（￥/月）Total lost/month 160,00

41、0.0 3.陽性不穩定（I）母豬場總損失（￥/月）Part 3：Total lost in 1000 sow inventory F2W farm per month 總損失（￥/月）Ecnomic lost from PRRSV positive unstable（I）versus stable (￥)173,980.8 1.研究背景及目的Research background and objective 2.2021Q4-2022Q4全國PRRSV普查數據The prevalent evolution of PRRSV in China from Q4 2021 to Q4 20223.P

42、RRSV陽性不穩定(I)對生產成績的影響 PRRSV positive unstable(I)impact on abortions and weaned piglets compared with PRRSV stable(II)farms4.影響PRRSV多樣性及影響PRRSV陽性不穩定(I)的因素分析The factors impact on genetic diversity of PRRSV and farm positive unstable(I)5.總結及致謝 Take home message&Acknowledgement 主要內容主要內容 Topics數據引自“百場計劃”項

43、目 data cited from“Century Project”豬繁殖與呼吸綜合征以下簡稱“藍耳病或PRRS”porcine reproductive and respiratory syndrome is abbreviated to PRRS in the following content 1.研究中豬場信息匯總 Basic Information of farms involved in this study母豬存欄 Sow inventory分娩到斷奶F2W分娩到其它Others總計Total1000217191000111324總計Total133043母豬存欄 Sow inv

44、entory外源引種External Introduction自繁自養Self-breeding自繁自養（一年內引種）Self-breeding(with pigs for breeding introduced in a year)總計Total10004150191000814224總計Total1229243注：Note本研究板塊僅包括連續送檢4次/個月的豬場This research only includes swine farms that have continuously submitted samples for inspection equal and more than

45、4 times/month后續把自繁自養（一年內有引種）納入到外源引種類別中Self breeding(introduced in one year)will be included later to external introduction.4.1 后備引入方式與藍耳病毒株多樣性及等級的關系Gilt introduction way impact on genetic diversity of PRRS and PRRS status 01234總計Total外源引種（場數）External introduction(farms)0463114自繁自養（場數）Self-breeding(f

46、arms)51770029總計Total521133143后備引種方式vs.場內毒株多樣性Gilt introduction mode and genetic diversity of PRRS不穩定I-AUnstable I-A不穩定I-BUnstable I-B趨于穩定IITend to be stable II穩定-IIIStable-III總計Total外源引種External introduction714214自繁自養Self-breeding4471429總計Total 11511164350%14%7%14%29%24%14%48%外源引種External introducti

47、on自繁自養Self-breeding不穩定I-AUnstable I-A不穩定I-BUnstable I-B趨于穩定IITend to be stable II穩定-IIIStable-III后備引種方式vs.豬場藍耳病類型Gilt introduction mode and farm PRRS statusx=2.1*x=1.1數據統計及分析使用GraphPad Prism 9.3GraphPad Prism 9.3 for data statistics and analysis*p0.05;*p0.01;*p0.001x=1.4野毒株數野毒株數/場場Number of wild str

48、ains/farm總計總計Total外源引種外源引種External introduction自繁自養自繁自養Self-breeding01234總計Total 10002124101910003992124總計Total 521133143不穩定I-AUnstable I-A不穩定I-BUnstable I-B趨于穩定IITend to be stable II穩定-IIIStable-III總計Total 100050861910006531024總計Total 11511164326%25%21%42%13%32%42%10001000不穩定I-AUnstable I-A不穩定I-BUn

49、stable I-B趨于穩定IITend to be stable II穩定-IIIStable-III4.2 豬場規模與藍耳病毒株多樣性及等級的關系No significant differences between sow inventory and genetic diversity and PRRS status in this study豬場規模vs.場內毒株多樣性 Sow inventory and Genetic diversity of PRRS 豬場規模vs.豬場藍耳病類型 Sow inventory and farm PPRS status數據統計及分析使用GraphPad

50、 Prism 9.3GraphPad Prism 9.3 for statistics and analysisNS:無統計學意義NS:Not statistically significantx=1.2NSx=1.5野毒株數野毒株數/場場Number of wild strains/farm1000100001234總計Total 分娩到斷奶F2W3451013分娩到其它Others21782130總計Total 521133143不穩定I-AUnstable I-A不穩定I-BUnstable I-B趨于穩定IITend to be stable II穩定-IIIStable-III總計T

51、otal分娩到斷奶F2W332513分娩到其它Others8291130總計Total11511164323%27%23%7%15%30%38%37%分娩到斷奶分娩到其它不穩定I-AUnstable I-A不穩定I-BUnstable I-B趨于穩定IITend to be stable II穩定-IIIStable-III4.3 豬場類型與藍耳病毒株多樣性及等級的關系No significant differences between farm type and genetic diversity and PRRS status in this study豬場類型 vs.場內毒株多樣性 Fa

52、rm type and genetic diversity of PRRS豬場類型vs.豬場藍耳病類型 Farm type and farm PRRS status數據統計及分析使用GraphPad Prism 9.3GraphPad Prism 9.3 for statistics and analysisNS:無統計學意義NS:not statistically significantx=1.3NSx=1.4野毒株數野毒株數/場場Number of wild strains/farm分娩分娩-斷奶斷奶Delivery-weaning分娩分娩-其它其它Delivery-otherOthers

53、F2W32.8%10.2%14.1%43.0%17.8%11.9%11.1%52.6%不穩定I-A不穩定I-B趨于穩定II穩定III連續生產批次化生產Batch production4.4 批次化生產可提高PRRSV等級Batch-production system is benefit on PRRS status improvement compared with continuous-production 結論 Take home message1.2021Q4到2022Q4期間，國內PRRSV的感染壓力依舊較大 PRRSV still in high prevalence in Chi

54、na,manifested by 野毒樣本檢出率24%，野毒場檢出率58%24%field PRRSV PCR positive reactions,meanwhile 58%farms in this study were found filed PRRSV circulating49%的場次存在早期感染（3-5日齡仔豬）；74%場次仔豬斷奶前野毒轉陽 49%of the farms initially infected by field isolate in 3-5 days old piglets,74%of the farms were infected before weaned.2

55、.與陽性穩定（II）場比陽性不穩定(I)豬場 Compared with PRRSV positive stable(II)，PRRSV positive unstable(I)will result in 平均每千頭母豬月流產數多6.4窩，窩均斷奶仔豬數少1.6頭 6.4 more abortions/month/thousand sows and 1.6 less weaned piglets/litter平均每千頭母豬月損失17.4萬元￥174K losses/month/thousand sows 3.后備引入方式及批次化管理是造成PRRSV場內毒株多樣性及不穩定的主要因素 Inclu

56、ding gilt introduction and batches management are main impactors for PRRSV diversity and unstable status外源引種場野毒多樣性多1.4株/場，陽性不穩定（I）場比例多29%External introduction resulted in 1.4 more PRRSV isolates diversity and 29%more PRRSV positive unstable(I)farms批次化管理陽性穩定場多9.6%，不穩定豬場少13.3%Batch production manageme

57、nt is capable in PRRSV status improvement致謝 Acknowledgement勃林格殷格翰所有同事的支持 All colleagues of BI全國139個規?；i場合作伙伴的信任Partners of the 139 scaled farms in China中國農業大學周磊副教授及團隊 Zhou Lei,associate professor of China Agricultural University中國農業科學院哈爾濱獸醫研究所豬病綜合防控團隊田志軍、張洪亮及周國輝研究員Comprehensive prevention and contro

58、l team of pig disease,Harbin Institute of veterinary medicine,Chinese Academy of Agricultural Sciences山東農業大學王剛教授及團隊 Professor Wang Gang and his team of Shandong Agricultural University廣東農科院動物衛生研究所張建峰副所長及劉志成老師及團隊 Zhang Jianfeng,deputy director of Institute of animal health,Guangdong Academy of Agricu

59、ltural Sciences,and teacher Liu Zhicheng and his team.江蘇科技大學張振東副教授及團隊 Zhang Zhendong,associate professor and his team of Jiangsu University of science and technology感謝李曼大會會務組及評委專家給與展示研究成果的機會 Thanks to the conference fairs group and committee of Leman conference for the opportunity to share the research results.“百場計劃”合作伙伴“Century Project”Partners5所高校及研究所 5 universities and research institutes139個合作伙伴 139 farms participant in