三個皮匠報告
政策庫
new
付費
搜索

Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割-行業數據

Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割
截至 2011 年，組成 CRISPR/Cas9 系統的三個基本元件 crRNA、tracrRNA 和Cas9 已經全部被發現，它們各自的重要功能也都基本得到了證實， CRISPR/Cas 系統的誕生，只差把這三個基本元件組合在一起并使其發揮基因編輯的功能。
行業數據 下載Excel 下載圖片 原圖定位
圖片屬性
圖片格式：PNG 圖片大?。?06KB 圖片尺寸：1770*782
同報告圖片
 / 54
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第1頁
fCDlm77ooaggIHwg5o+P6L+wICB8CnwgLS0tIHwgLS0tIHwKfCBDYXM5IHByb2dyYW1tZWQgYnkgY3JSTkE6dHJhY3JSTkEgZHVwbGV4IHwg5YyF5ZCrY3JSTkHlkox0cmFjclJOQeeahOWkjeWQiOeJqSB8CnwgQ2FzOSBwcm9ncmFtbWVkIGJ5IHNpbmdsZSBjaGltZXJpYyBSTkEgfCDljIXlkKtjclJOQS10cmFjclJOQeW1jOWQiOS9k+eahOWNleS4gFJOQSB8CgrotYTmlpnmnaXmupDvvJpTY2llbmNlLCDlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第2頁
5oqx5q2J77yM5oiR5peg5rOV5o+Q5Y+W5Zu+54mH5Lit55qE5pWw5o2u5oiW55Sf5oiQ6KGo5qC844CC6K+35oKo5o+Q5L6b5paH5a2X54mI5pys55qE6LWE5paZ77yM5oiR5Lya5b6I5LmQ5oSP5biu5Yqp5oKo5pW055CG5oiQ6KGo5qC844CC
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第3頁
fCDluo/lj7cgfCDph43opoHlo7DmmI4gfAp8LS0tLS0tfC0tLS0tLS0tLS18CnwgMTMgICB8IOivt+WKoeW/hemYheivu+aKpeWRiuacq+mhteeahOmHjeimgeWjsOaYjiB8CgrotYTmlpnmnaXmupDvvJrlm77niYflhoXlrrnjgII=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第4頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第5頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第6頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第7頁
fCBOdWNsZWFyIEROQSB8IE1pdG9jaG9uZHJpYWwgRE5BIHwKfC0tLS0tLS0tLS0tLS0tfC0tLS0tLS0tLS0tLS0tLS0tLS0tLXwKfCAzLDAwMCwwMDAsMDAwIGJhc2UgcGFpcnMgfCAxNiw1MDAgYmFzZSBwYWlycyB8
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第8頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第9頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第10頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第11頁
fCDlsLzlronlvrfnibnkurogfCDkuLnlsLzntKLnk6bkurogfCDnjrDku6PkurogfAp8LS0tLS0tLS0tLS0tLXwtLS0tLS0tLS0tLS0tfC0tLS0tLS0tLS0tLS18Cnwg57qmNDIuNeS4h+W5tOWJjSB8IOe6pjQyLjXkuIflubTliY0gfCDnuqY2NeS4h+W5tOWJjSB8CgrotYTmlpnmnaXmupDvvJpMdWN5IFJlYWRpbmctSWtrYW5kYSBhbmQgTWVycmlsIFNoZXJtYW4vUXVhbnRhIE1hZ2F6aW5lLCDlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第12頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第13頁
55Sx5LqO5oKo5o+Q5L6b55qE5Zu+54mH5YaF5a656L6D5Li65aSN5p2C77yM5oiR5peg5rOV55u05o6l5o+Q5Y+W5YW25Lit55qE5pWw5o2u55Sf5oiQ6KGo5qC844CC5aaC5p6c5oKo6IO95o+Q5L6b5pu05riF5pmw55qE5paH5a2X5L+h5oGv5oiW5pWw5o2u77yM5oiR5bCG5b6I5LmQ5oSP5biu5Yqp5oKo55Sf5oiQ6KGo5qC85bm25Zyo5LiL5pa55bGV56S66LWE5paZ5p2l5rqQ44CC
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第14頁
5aW955qE77yM5Lul5LiL5piv5oKo5Zu+54mH5Lit55qE5pWw5o2u5Lul5Y+K6LWE5paZ5p2l5rqQ77yaCgp8IOaXtumXtCB8IOagh+W/l+aAp+S6i+S7tiB8CnwtLS0tLS18LS0tLS0tLS0tLS0tLS0tLS0tfAp8IDE5NTMgfCBETkHlj4zliIblrZDonrrml4vnu5PmnoTooqvlj5HnjrAgfAp8IDE5NzAgfCDlkLTnkZ7pppblhYjlj5HmmI7kuoZETkHmtYvluo/mlrnms5Xku6Xlj4rlhbbku5bkuIDkuptETkHlhYvpmobmioDmnK8gfAp8IDE5NzcgfCDmoZHmoLzlj5HmmI5ETkHlj4zohLHmsKfpk77nu4jmraLms5UgfAp8IDE5ODEgfCDnrKzkuIDmrKHmtYvlvpfkurrnsbvnur/nspLkvZPln7rlm6Dnu4TmtYvluo8gfAp8IDE5ODYgfCBBQknlhazlj7jln7rkuo7moZHmoLzms5Xlj5HmmI5BQkkgMzcwQea1i+W6j+S7qiB8CnwgMTk5MCB8IOKAnOS6uuexu+WfuuWboOe7hOiuoeWIkuKAneWQr+WKqCB8CnwgMTk5NSB8IOesrOS4gOasoeW+l+WIsOWujOaVtOeahOe7huiPjOWfuuWboOe7hO+8muWXnOihgOa1geaEn+iPjCB8CnwgMTk5NiB8IOesrOS4gOasoeW+l+WIsOWujOaVtOeahOecn+aguOeUn+eJqeWfuuWboOe7hO+8mumFv+mFkumFteavjSB8CnwgMjAwMSB8IOS6uuexu+WfuuWboOe7hOiuoeWIkuW3peS9nOiNieWbvuWPkeihqCB8CnwgMjAwNSB8IFJvY2hl5Y+R5biD56ys5LiA5Y+w5LqM5Luj5rWL5bqP5Luq77yaNDU0IEdTIDIwIHwKfCAyMDA3IHwgSWxsdW1pbmHlj5HluIPkuozku6PmtYvluo/ku6pHZW5ldGljIEFuYWx5emVyIDIgfAp8IDIwMDggfCDkurrnsbvlvq7nlJ/niannu4TorqHliJLlkK/liqggfAp8IDIwMTEgfCBQYWNCaW/lhazlj7jlj5HluIPkuInku6PmtYvluo/ku6ogfAp8IDIwMTQgfCBPTlTlhazlj7jlj5HluIPnurPnsbPlrZTmtYvluo8gfAp8IDIwMTcgfCDljY7lpKfmmbrpgKDlhazluIPpq5jpgJrph4/mtYvluo/ns7vnu59NR0lTRVEtMjAwMOWPik1HSVNFUS0yMDAgfAp8IDIwMTkgfCDljY7lpKfmmbrpgKDlhazluIPmtYvluo/ku6pNR0lTRVEtVDfjgIHlhajnkIPpppbliJvkuK3ojYnoja/ln7rlm6DmtYvluo/ogYzog73pibTlrprku6pITUJJLUczMCB8CnwgMjAxOSB8IOS6uuexu+W+rueUn+eJqee7hOiuoeWIkuesrOS6jOmYtuautUlITVDlrozmiJAgfAp8IDIwMjAgfCDljY7lpKfmmbrpgKDlhazluIPmtYvluo/ku6pNR0lTVE8tNzAwMO+8jDQw5YiG6ZKf5YaF5a6M5oiQMTky5L6L5qC35pys6Ieq5Yqo5YyW57K+5YeG5YiG6KOFIHwKfCAyMDIyIHwg5aGr6KGl5Lq657G75Z+65Zug57uE5pyA5ZCOOCXnmoTnqbrnmb3vvIzov4Tku4rmnIDlrozmlbTnmoTkurrnsbvln7rlm6Dnu4RUMlQtQ0hNMTPmtYvluo/nu5PmnpzlhazluIMgfAoK6LWE5paZ5p2l5rqQ77ya5Y2O5aSn5pm66YCg5a6Y572R77yM5Zu96IGU6K+B5Yi456CU56m25omA
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第15頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第16頁
5oqx5q2J77yM5oiR5peg5rOV5o+Q5Y+W5Zu+54mH5Lit55qE5pWw5o2u5oiW55Sf5oiQ6KGo5qC844CC6K+35oKo5o+Q5L6b5paH5a2X5o+P6L+w5oiW5YW25LuW5L+h5oGv77yM5oiR5bCG5bC95Yqb5biu5Yqp5oKo44CC
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第17頁
5qC55o2u5Zu+54mH5Lit55qE5pWw5o2u77yM5Lul5LiL5piv6KGo5qC85bGV56S677yaCgp8IOWuouaIt+exu+WeiyAgICAgICAgICB8IOWNoOavlCAgfAp8LS0tLS0tLS0tLS0tLS0tLS0tfC0tLS0tLXwKfCDlrabmnK/noJTnqbYgICAgICAgICAgfCA1MC42JXwKfCDkuLTluornoJTnqbYgICAgICAgICAgfCAxOS40JXwKfCDljLvpmaLlkozor4rmiYAgICAgICAgIHwgMTUuMiV8Cnwg5Yi26I2v5Y+K55Sf54mp5oqA5pyv5YWs5Y+4IHwgOS45JSB8Cnwg5YW25LuW57G75Z6L77yI5Yac5Lia44CB546v5aKD562J77yJIHwgNC45JSB8CgrotYTmlpnmnaXmupDvvJpHcmFuZCBWaWV3IFJlc2VhcmNo77yM5Zu96IGU6K+B5Yi456CU56m25omA
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第18頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第19頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第20頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第21頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第22頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第23頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第24頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第25頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第26頁
5aW955qE77yM5Lul5LiL5piv6K+l5Zu+54mH5Lit55qE5pWw5o2u5Y+K5a+55bqU55qE6KGo5qC877yM5bm25Zyo5LiL5pa55bGV56S65LqG6LWE5paZ5p2l5rqQ77yaCgp8ICDml7bpl7TngrkgfCDkuovku7YgfAp8IC0tLSB8IC0tLSB8CnwgMjDkuJbnuqo2MOW5tOS7o+i1tyB8IOWWueWVieexu+aKl+eWn+WkseaViOOAgeS4reWbvemlseWPl+eWn+eWviB8CnwgMTk2OeW5tCB8IOWxoOWRpuWRpuaJv+aOpeWbveWutuKAnDUyM+KAnemhueebriB8CnwgMTk3MuW5tCB8IOWxoOWRpuWRpuWboumYn+WPkeeOsOmdkuiSv+e0oCB8CnwgMTk4MOW5tCB8IOmdkuiSv+e0oOaIkOWKn+ayu+aEiOeWn+eWvuaCo+iAhe+8jOeWn+eWvuS4pemHjea1geihjOaDheWGteW+l+WIsOaOp+WItiB8CnwgMTk5MeW5tCB8IOS4reWbveWGm+S6i+WMu+WtpuenkeWtpumZouW8gOWPkeeahOWkjeaWueiSv+eUsumGmumAmui/h+ivuuWNjui1sCB8CnwgMjAwMOW5tCB8IOWFqOWbvei+vuWIsOKAnOWfuuacrOa2iOeBreeWn+eWvuKAneagh+WHhu+8jOWPkeeXheeOh+mZjeS9jiB8CnwgMjAwNeW5tCB8IOmdkuiSv+e0oOiAkOiNr+aAp+mXrumimOWcqOafrOWflOWvqOilv+mDqOmmluasoeiiq+WPkeeOsCB8CnwgMjAwNuW5tCB8IFdUT+Wuo+W4g+mdkuiSv+e0oOiBlOWQiOeWl+azle+8iEFDVO+8ieS9nOS4uuayu+eWl+eWn+eWvueahOS4gOe6v+eWl+azlSB8CnwgMjAxNeW5tCB8IOWxoOWRpuWRpuWboumYn+WPkeeOsOmdkuiSv+e0oO+8jOiOt+W+l+ivuui0neWwlOeUn+eQhuWtpuaIluWMu+WtpuWlliB8CnwgMjAxOeW5tCB8IOWxoOWRpuWRpuWboumYn++8mumdkuiSv+e0oOaKl+iNr+aAp+KAneetieeglOeptuiOt+aWsOeqgeegtO+8jOWPjOawoumdkuiSv+e0oOWvuemrmOWPmOW8guaAp+eahOe6ouaWkeeLvOeWrueahOayu+eWl+aViOaenOeLrOeJuSB8CnwgMjAyMOW5tCB8IOS4reWbveWunueOsOKAnOa2iOmZpOeWn+eWvuKAneebruaghyB8CgrotYTmlpnmnaXmupDvvJrmlofnjK7igJzlsaDlkablkabvvJrkuI3kuIDmoLfnmoTnmoTmlYXkuovvvIzkuI3lubPlh6HnmoTmiJDlsLHigJTigJTlgaXlurflt6jmmJ/lho3op4Llr5/igJ3vvIzlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第27頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第28頁
5qC55o2u5Zu+54mH5Lit55qE5p+x54q25Zu+77yM5Y+v5Lul5o+Q5Y+W5Lul5LiL5pWw5o2u5bm255Sf5oiQ6KGo5qC877yaCgp8IOWkhOaWueexu+WeiyAgICAgICB8IOaVsOmHjyB8CnwtLS0tLS0tLS0tLS0tLS0tfC0tLS0tLXwKfCDkuLTluornu4/pqozmlrkgICAgIHwgMTQgICB8Cnwg5Lit6I2v5o+Q5Y+W54mpICAgICB8IDcgICAgfAp8IOe7j+WFuOWQjeaWueWMluijgeaWuSB8IDYgICAgfAp8IOWMu+mZoumZouWGheWItuWJgiAgIHwgMiAgICB8Cnwg57uP5YW45ZCN5pa5ICAgICAgIHwgMiAgICB8CgrotYTmlpnmnaXmupDvvJrlm73lrrboja/lk4Hnm5HnnaPnrqHnkIblsYDoja/lk4HlrqHor4TkuK3lv4PvvIzlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第29頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第30頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第31頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第32頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第33頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第34頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第35頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第36頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第37頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第38頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第39頁
fCDlubTku70gfCDnp5HlrablrrYgfCDlhoXlrrkgfAp8LS0tLS0tfC0tLS0tLS0tLS0tLS0tLS18LS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS18CnwgMTk4NyB8IFlvc2hpenVtaSBJc2hpbm8gfCDpppbmrKHlnKjlpKfogqDmnYboj4zkuK3op4Llr5/liLDnibnmrornmoTph43lpI3luo/liJcgfAp8IDE5OTMgfCBGcmFuc2lzY28gSi4gTS4gTW9qaWNhIHwg5Zyo5Zyw5Lit5rW35Zec55uQ6I+M5Lit6KeC5a+f5Yiw54m55q6K55qE6YeN5aSN5bqP5YiXIHwKfCAxOTk1IHwgRnJhbnNpc2NvIEouIE0uIE1vamljYSB8IOWcqOayg+awj+WXnOebkOWvjOmltuiPjOWXnOebkOWPpOiPjOS4reinguWvn+WIsOexu+S8vOmHjeWkjeW6j+WIlyB8CnwgMjAwMCB8IEZyYW5zaXNjbyBKLiBNLiBNb2ppY2EgfCDlnKjnu5PmoLjliIbmnp3mnYboj4znrYkyMOS9meenjeW+rueUn+eJqeS4reWPkeeOsOexu+S8vOW6j+WIl++8jOW5tuWRveWQjeS4ulNSU1JTIHwKfCAyMDAyIHwgUnV1ZCBKYW5zZW4gfCDpppbmrKHlsIbov5nkuKrph43lpI3luo/liJflkb3lkI3kuLpDUklTUFLvvIzlubbpibTlrprkuobll5zng63pk77nkIPoj4zkuI7phb/ohJPpk77nkIPoj4znmoRjYXMxLTTln7rlm6AgfAp8IDIwMDUgfCBGcmFuc2lzY28gSi4gTS4gTW9qaWNhIHwg5ZyoSW4gU2lsaWNv5bGC6Z2i5Y+R546w5LqGQ1JJU1BS5LiO5Zms6I+M5L2T55qE5YWz57O7IHwKfCAyMDA3IHwgUGhpbGlwcGUgSG9ydmF0aCB8IOmmluasoemAmui/h+WunumqjOivgeaYjuWOn+aguOeUn+eJqeS4rUNSSVNQUi9DYXPns7vnu5/nmoTlhY3nlqvmnLrliLYgfAp8IDIwMDggfCBKb2huIHZhbmRlciBPb3N0IHwg6aaW5qyh6YCa6L+H56iL5bqP6K6+6K6h5Z+65LqOQ1JJU1BS55qE5YWN55ar5py65Yi255qE5a6e6aqMIHwKfCAyMDA4IHwgTHVjaWFubyBNYXJyYWZmaW5pIHwg6K+B5piOQ1JJU1BS55qE6Z225qCH5pivRE5BIHwKfCAyMDEwIHwgU3lsdmFpbiBNb2luZWF1IHwg5Y+R546w5Zec54Ot6ZO+55CD6I+M5Lit55qEQ1JJU1BSL0Nhcznns7vnu5/mmK/nlLFjclJOQXPmjIflvJXlubbkuJTlnKhETkHkuK3pgKDmiJDlj4zpk77mlq3oo4IgfAp8IDIwMTEgfCBFbW1hbnVlbGxlIENoYXJwZW50aWVyIHwg5Y+R546wdHJhY3JSTkEgfAp8IDIwMTEgfCBWaXJnaW5panVzIFNpa3NueXMgfCDpppbmrKHlnKjov5znvJjnu4boj4zniannp43kuK3ph43lu7pDUklTUFLvvIzlubbor4HmmI5DYXM555qE6YeN6KaB5oCnIHwKfCAyMDEyIHwgRG91ZG5h5LiOQ2hhcnBlbnRpZXIgfCDpppbmrKHliKnnlKhDUklTUFIvQ2Fz57O757uf5Zyo5L2T5aSW5a+5RE5B6L+b6KGM5YiH5YmyIHwKfCAyMDEyIHwgVmlyZ2luaWp1cyBTaWtzbnlzIHwg5Yip55SoQ1JJU1BSL0Nhc+ezu+e7n+WcqOS9k+WkluWvuUROQei/m+ihjOWIh+WJsiB8CnwgMjAxMyB8IEZlbmcgWmhhbmcgfCDpppbmrKHliKnnlKhDUklTUFIvQ2Fz57O757uf5a6e546w5a+55Lq657G757uG6IOe6L+b6KGM5Z+65Zug57uE57yW6L6RIHwKfCAyMDEzIHwgR2VvcmdlIE0uIENodXJjaCB8IOmmluasoeWIqeeUqENSSVNQUi9DYXPns7vnu5/lrp7njrDlr7nkurrnsbvnu4bog57ov5vooYzln7rlm6Dnu4TnvJbovpEgfAp8IDIwMTMgfCBKZW5uaWZlciBBLiBEb3VkbmEgfCDliKnnlKhDUklTUFIvQ2Fz57O757uf5a6e546w5a+55Lq657G757uG6IOe6L+b6KGM5Z+65Zug57uE57yW6L6RIHwKCui1hOaWmeadpea6kO+8muWMl+S6rOWkp+Wtpi3lpKflrabljJblrabvvIzlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第40頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第41頁
fCDlm77ooaggIHwg5o+P6L+wICB8CnwgLS0tIHwgLS0tIHwKfCBDYXM5IHByb2dyYW1tZWQgYnkgY3JSTkE6dHJhY3JSTkEgZHVwbGV4IHwg5YyF5ZCrY3JSTkHlkox0cmFjclJOQeeahOWkjeWQiOeJqSB8CnwgQ2FzOSBwcm9ncmFtbWVkIGJ5IHNpbmdsZSBjaGltZXJpYyBSTkEgfCDljIXlkKtjclJOQS10cmFjclJOQeW1jOWQiOS9k+eahOWNleS4gFJOQSB8CgrotYTmlpnmnaXmupDvvJpTY2llbmNlLCDlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第42頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第43頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第44頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第45頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第46頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第47頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第48頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第49頁
fCDnlqvoi5flhazlj7ggICAgICAgfCAyMDIx5bm06ZSA5ZSu6aKd77yI5Lq/576O5YWD77yJIHwgMjAyMuW5tOS4iuWNiuW5tOmUgOWUrumine+8iOS6v+e+juWFg++8iSB8CnwtLS0tLS0tLS0tLS0tLS0tfC0tLS0tLS0tLS0tLS0tLS0tLS0tLS18LS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tfAp8IOi+ieeRni9CaW9OVGVjaCAgfCAzNjggICAgICAgICAgICAgICAgICB8IDIyMSAgICAgICAgICAgICAgICAgICAgICAgfAp8IE1vZGVybmEgICAgICAgIHwgMTc3ICAgICAgICAgICAgICAgICAgfCAxMDUgICAgICAgICAgICAgICAgICAgICAgIHwKCgrotYTmlpnmnaXmupDvvJrlhazlj7jlhazlkYrvvIzlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第50頁
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
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第51頁
fCDlm73lrrYgICB8IOiOt+WlluS6uuaVsCB8CnwtLS0tLS0tLXwtLS0tLS0tLXwKfCDnvo7lm70gICB8IDEwMCAgICB8Cnwg6Iux5Zu9ICAgfCAzMCAgICAgfAp8IOW+t+WbvSAgIHwgMjAgICAgIHwKfCDms5Xlm70gICB8IDEwICAgICB8Cnwg55Ge5YW4ICAgfCAxMCAgICAgfAp8IOa+s+Wkp+WIqeS6miB8IDUgICAgICB8Cnwg55Ge5aOrICAgfCA1ICAgICAgfAp8IOWlpeWcsOWIqSAgfCA1ICAgICAgfAp8IOS4uem6piAgIHwgNSAgICAgIHwKfCDmhI/lpKfliKkgIHwgNSAgICAgIHwKfCDlhbbku5YgICB8IDIwICAgICB8CgrotYTmlpnmnaXmupDvvJror7rotJ3lsJTlpZblrpjnvZHvvIzlm73ogZTor4HliLjnoJTnqbbmiYA=
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第52頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第53頁
fCDlubTku70gfCDplIDllK7pop3vvIjkur/nvo7lhYPvvIkgfAp8LS0tLS0tfC0tLS0tLS0tLS0tLS0tLS0tLXwKfCAyMDE4IHwgMTAgICAgICAgICAgICAgICB8CnwgMjAyMSB8IDMwICAgICAgICAgICAgICAgfAoKCui1hOaWmeadpea6kO+8mkJsb29tYmVyZ++8jOWbveiBlOivgeWIuOeglOeptuaJgA==
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第54頁
Cas9由crRNA：trancrRNA（左）或單鏈sgRNA（右）引導進行切割_第55頁
所屬報告： 醫藥生物行業：諾貝爾獎持續惠及人類福祉-221009（47頁）.pdf
打包全文圖表

相關數據

最新數據
聯系我們
  • 0731-84720580
  • sgpjbg002
  • 工作日 9:30 - 18:00
關于我們
侵權處理
關于我們

三個皮匠報告專業的行業報告下載站，每日更新，歡迎大家關注！

copyright@2008-2013 長沙景略智創信息技術有限公司版權所有
網站備案/許可證號：湘B2-20190120

客服
商務合作
小程序
服務號
折疊
午夜网日韩中文字幕,日韩Av中文字幕久久,亚洲中文字幕在线一区二区,最新中文字幕在线视频网站