三個皮匠報告
政策庫
new
付費
搜索

HER2雙表位ADC（JSKN003）的結構和作用機制-行業數據

HER2雙表位ADC（JSKN003）的結構和作用機制
HER2雙表位ADC（JSKN003）的結構和作用機制
JSKN003 是由康寧杰瑞開發的靶向 HER2 雙表位的抗體偶聯藥物（ADC），通過其糖基定點偶聯技術平臺，將拓撲異構酶 I 抑制劑連接至抗 HER2 雙特異性抗體 KN026 的 N 糖基化位點，可通過細胞內吞釋放拓撲異構酶Ⅰ抑制劑，進而發揮抗腫瘤作用。
行業數據 下載Excel 下載圖片 原圖定位
圖片屬性
圖片格式：PNG 圖片大?。?111KB 圖片尺寸：2350*778
同報告圖片
 / 25
HER2雙表位ADC（JSKN003）的結構和作用機制_第1頁
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
HER2雙表位ADC（JSKN003）的結構和作用機制_第2頁
5aW955qE77yM5Lul5LiL5piv6K+l5Zu+6KGo5Lit55qE5pWw5o2u5pW055CG5oiQ55qE6KGo5qC877yaCgp8IOmhueebriB8IFRLSSByZXNpc3RhbmNlIG9ubHkgfCBUS0kgKyBQbGF0aW51bSByZXNpc3RhbmNlIHwKfCA6LS06IHwgOi0tOiB8IDotLTogfAp8IDAuNm1nL2tnIHwgIHwgIHwKfCAxLjhtZy9rZyB8ICB8ICB8CnwgNC4ybWcva2cgfCAgfCAgfAp8IDQuOG1nL2tnIHwgIHwgIHwKfCA1LjZtZy9rZyB8ICB8CnwgNi40bWcva2cgfCAgfAoK6LWE5paZ5p2l5rqQ77yaQUFDUjIwMjXvvIzlhazlj7jlrpjlvq7vvIzlpKrlubPmtIvor4HliLjmlbTnkIY=
HER2雙表位ADC（JSKN003）的結構和作用機制_第3頁
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
HER2雙表位ADC（JSKN003）的結構和作用機制_第4頁
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
HER2雙表位ADC（JSKN003）的結構和作用機制_第5頁
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
HER2雙表位ADC（JSKN003）的結構和作用機制_第6頁
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
HER2雙表位ADC（JSKN003）的結構和作用機制_第7頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第8頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第9頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第10頁
fCBIRVIyK+S5s+iFuueZjDFM77yIbj01N++8iSB8IEhFUjIr5Lmz6IW655mM5paw6L6F5Yqp77yIbj0zMO+8iSB8IEhFUjIr6IOD55mM77yITj0zOe+8iSB8CnwtLS0tLS0tLS0tLS0tLS0tLS0tLS0tfC0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tfC0tLS0tLS0tLS0tLS0tLS0tLXwKfCDnu4TlkIjnlpfms5UgICAgICAgICAgICAgIHwgK+WMlueWlyAgICAgICAgICAgICAgICAgICAgfCAr5YyW55aXICAgICAgICAgICAgfCAr5YyW55aXICAgICAgICAgICAgfAp8IOaAu+eUn+WtmOacn09TICAgICAgICAgICB8IDc3Ljkl77yIMzBt77yJICAgICAgICAgICAgIHwgLSAgICAgICAgICAgICAgICB8IDEzLjIgICAgICAgICAgICAgfAp8IOS4reS9jeaXoOi/m+WxleeUn+WtmOacn1BGUyAgfCAyNi45be+8iOacquaIkOeGn++8iSAgICAgICAgICB8IC0gICAgICAgICAgICAgICAgfCA4LjZtICAgICAgICAgICAgIHwKfCDlrqLop4LnvJPop6PnjodPUlIgICAgICAgIHwgNzYuNCUgICAgICAgICAgICAgICAgICAgIHwgNTYuNyXvvIh0cENS77yJICAgIHwgNDAlICAgICAgICAgICAgICB8Cnwg4omlM+e6p0FFICAgICAgICAgICAgICAgfCBLTjAyNuebuOWFs1RFQUUgNDAuNCUgICAgIHwgVEVBRSA1My4zJSAgICAgICB8IFRFQUUgNzQuNCUgICAgICAgfAp8IOWPkeihqOacn+WIiiAgICAgICAgICAgICAgfCAyMDIzIEVTTU8gICAgICAgICAgICAgICAgfCAyMDIzIEVTTU8gICAgICAgIHwgMjAyNCBFU01PICAgICAgICB8CgrotYTmlpnmnaXmupDvvJrlhazlj7jlrpjnvZHvvIzlhazlj7jkuqTmtYHmnZDmlpnvvIzlpKrlubPmtIvor4HliLjmlbTnkIY=
HER2雙表位ADC（JSKN003）的結構和作用機制_第11頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第12頁
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
HER2雙表位ADC（JSKN003）的結構和作用機制_第13頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第14頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第15頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第16頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第17頁
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
HER2雙表位ADC（JSKN003）的結構和作用機制_第18頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第19頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第20頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第21頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第22頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第23頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第24頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第25頁
HER2雙表位ADC（JSKN003）的結構和作用機制_第26頁
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
所屬報告： 石藥集團-港股公司研究報告-八大創新平臺進入兌現期重磅品種啟動關鍵臨床-250516（30頁）.pdf
打包全文圖表

相關數據

最新數據
聯系我們
  • 0731-84720580
  • sgpjbg002
  • 工作日 9:30 - 18:00
關于我們
侵權處理
關于我們

三個皮匠報告專業的行業報告下載站，每日更新，歡迎大家關注！

copyright@2008-2013 長沙景略智創信息技術有限公司版權所有
網站備案/許可證號：湘B2-20190120

客服
商務合作
小程序
服務號
折疊
午夜网日韩中文字幕,日韩Av中文字幕久久,亚洲中文字幕在线一区二区,最新中文字幕在线视频网站