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曲妥珠與帕妥珠作用于HER2不同結構：家族受體二聚體化激活下游通路-行業數據

曲妥珠與帕妥珠作用于HER2不同結構：家族受體二聚體化激活下游通路
曲妥珠與帕妥珠作用于HER2不同結構：家族受體二聚體化激活下游通路
? HER2 受體胞外結構域（ECD，Extracellular Domain）包含 4 個部分，帕妥珠單抗與曲妥珠單抗分別結合與不同的部分（ECD2和 ECD4），可抑制不同 型的 HER家族受體二聚化，為曲帕雙妥雙靶 合可能提高 效的基礎醫學依據。
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曲妥珠與帕妥珠作用于HER2不同結構：家族受體二聚體化激活下游通路_第1頁
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所屬報告： 康寧杰瑞制藥-港股公司深度報告：ADC前沿探索差異化開發乳腺癌多亞型覆蓋大品種即將兌現-241216（28頁）.pdf
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