6.15 食品投融資+菲仕蘭+Urszula Kudla+英文.pdf

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1、 2021 FrieslandCampina IngredientsPrecision Fermentation:the future of food industry?精準發酵：食品行業的未來？Dr Urszula KudlaFrieslandCampina Ingredients,The NetherlandsFr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d

2、 i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t sAgenda for today:目錄：1.What is precision fermentation and where is it used?什么是精準發酵及使用場景？2.What are the commercial trends?商業趨勢洞察3.Ambitions

3、 and challenges to overcome雄心與挑戰4.Short introduction to FrieslandCampina Ingredients菲仕蘭食品配料簡介2Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr

4、 i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s替代乳制品的不同分支技術There are different sub-technologies falling under the umbrella dairy alternatives3Plant-basedCell-based/Proteins by FermentationMicrobe-basedPrecision FermentationCultured milkDescriptionP

5、roteins extracted from plantsDewatered whole microbial cells,rich in proteins.Proteins may be extracted if needed.Dairy identical proteins made by genetic modification of micro-organismHuman or bovine cells milked in a bioreactorInvestment in technologyBillions of euros900 M 1800 M45 MHighlightedpro

6、ducts currentlyon the marketNot on the market(yet)Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n

7、 t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s精準發酵的由來History of Precision FermentationPrecision fermentation is a technology that is already used for decades to produce many different types of molecules.Some examples are:4VitaminsPharmaceuticalsEnzymesHMOsFr i e s l a n d Ca m p i n a In g

8、r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s精準發酵為食品行業帶來無限潛能，例如乳蛋白替代物Precis

9、ion fermentation provides ample opportunities for the future,such as development of copies of dairy proteinsFinal productA protein powder containing pure animal-like protein(for example Lactoferrin)Purify proteinFermentationProduce protein with micro-organism in fermenterMicro-organismTake DNA fragm

10、ent of a dairy protein and introduce in micro-organismFr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i

11、 e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s精準發酵-發酵流程Precision fermentation Fermentation processThe micro-organism do not live on air only,they need many different components to grow and produce proteins.Cell growthSugarsWhat goes inNitrogenTrace elementsStarting cellsAirWhat comes ou

12、tDesired protein(1-3%)CellsBy-productsLeftover raw materialDNAA broth containing:Production of proteinProduct of by-productsFr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p

13、 i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s精準發酵：在未來可持續食品生產中的作用？Precision Fermentation:role in the future sustainable food production?7Precision fermentation does not require animals or fields.The ambition is to mak

14、e it sustainable,cost-effective and environmentally friendly and thus potentially transform food industry as well as agricultureFr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca

15、 m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s精準發酵的價格在過去幾十年呈指數級下降Price of precision fermentation has decreased exponentially over the last decadesWith current state of technology,application in food becomes possib

16、le.81.E+021.E+041.E+061.E+081.E+1019801985199019952000200520102015202020252030Competitive in MedicineCompetitive in CosmeticsCompetitive in MaterialsCompetitive in FoodPrecision FermentationLog($/kg protein)Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i

17、 e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s由于價格下降，發酵技術可用于食品，尤其是在美國Due to decreased price,fermentation technology can be used in foo

18、d products,especially in the US9Addition of heme in plant-based burgers for meaty flavor Fish oil from AlgaeFungi as replacementof meatFr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a

19、 n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t sAgenda for today:101.What is precision fermentation and where is it used?什么是精準發酵及使用場景？2.What are the commercial trends?商業趨勢洞察3.Ambitions and challenges to overc

20、ome雄心與挑戰4.Short introduction to FrieslandCampina Ingredients菲仕蘭食品配料簡介Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n

21、 a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s一些組織認為發酵將成為乳制品行業的技術顛覆者|兩個愿景：Some organizations foresee Fermentation as technologicaldisrupter for the dairy industry|Two visions:11Two visions on the role of Precision Fermentation in the future of dairy1.Four plausible scenar

22、ios for the future of the Dairy Industry|Tetra Pak2.Food and Agriculture Report RethinkXThe dairy landscape is shifting:the forecast what the dairy industry will look like in 20301Dairy EvolutionGreenDairyNew FusionBrave New FoodCow basedPlant basedLab grown2%5%35%50%Joint study:(2020)Precision Ferm

23、ented ProteinCow ProteinV.S.10-25xLess feedstock5xLess energy10 xLess water100 xLess land=Existential crisis=Modern revivalFr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p

24、i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t sCompanyInitiativePartners inclInvestmentprotein(microbe-based)$508mAlternative dairy proteins,incl.casein&whey.(precision fermentation)$711mDairy alternative proteins(preci

25、sion fermentation)$344mCheeses;focus on pizza cheese(precision fermentation)$29mprotein(microbe-based)$23mAlternative dairy products.”(precision fermentation)$54mBreastmilk proteins&HMO(precision fermentation and cultured milk)$40mDairy alternative(precision fermentation)$131m活躍在該領域的初創企業已經籌集了大量資金來促進

26、產品創新Start ups active in the field have raised enormous capital to catalyze product innovationsSome examples of companies active in the field of producing dairy components/alternatives US|2012US-2019GER|2019US|2014NL|2011US-2018Up until Feb23,companies focused on cell based alternative proteins have

27、raised more than$2.5 billion.Today,a long list of food technology firms/start-ups(35)are developing fermentation based dairy alternatives or components thereof.10+Partnerships have been announced between traditional and fermentation based dairy companies.An example is Tasman,a joint venture between

28、DSM and Fonterra.SIN|2019ISR|2019The rapid rise of cell-based products for alternative proteinsFr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s F

29、r i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s消費者對精密發酵產品的接受度上升Consumer acceptance for precision fermentation products13Zollman Thomas,O.,&Bryant,C.(2021).Dont Have a Cow,Man:Consumer Acceptance of Animal-Free Dairy Products in Five Countries.Fron

30、tiers in Sustainable Food Systems,5.https:/doi.org/10.3389/fsufs.2021.678491Dairy alternativesClean meat=Precision fermentationSignificantly higher likelihood of purchasing clean meat and plant-based meat in China and India compared to the USA(p 30mbabiesLACTOSEBASEPOWDERSWHEY PROTEINSGOS200 kBabies

31、 with special dietary needs hydrolysates50 mpatientscaseinate25mathletes&active lifestyle consumersPROTEINS30+different biological drugs and vaccines for treatment of a wide range of diseaseshydrolysates10-20%of all medicine tablets worldwideLACTOSEFr i e s l a n d Ca m p i n a In g r e d i e n t s

32、Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s與學術界和研究機構深度合作，為客戶和消費者提供健康解決方案We collaborate wi

33、th academia and institutes to bring better health to the people our customers serve23MEDCIAL CENTREUNIVERSITIESRadboud University Medical Centre HMO,protein supplementation related to recovery after surgeryAmsterdam University Medical Centre Dairy vs.plant-based protein in active agingUtrecht Univer

34、sityPrebiotics,protein analysisMaastricht UniversityPrebiotics,proteinWageningen UniversityMultiple topicsRESEARCH INSTITUTESNIZO food research Multiple topicsTNO researchMultiple topicsPrincess Maxima Medical Centre HMOEXAMPLE PROJECTSEnergy efficient milk sprayingNovel food processingRecycling nut

35、rientsWater to farm Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i

36、 n a In g r e d i e n t s隸屬于荷蘭皇家菲仕蘭，為生命各個階段提供專業產品和方案FrieslandCampina Ingredients is part of FrieslandCampina and focuses on specialised ingredients for all stages of life24High-quality basic dairy productsBranded products for specific nutritional needsSpecialised nutritional ingredients for all life

37、 stages and the pharma industryProfessionalHigh-quality products for out-of-home channelsConsumer DairyBrandsTradingSpecialised NutritionIngredientsFood&BeverageMorning/breakfastCheesePopulation growth in Asia&AfricaButter and cream for chefs and bakeries(Debic)Coffee(Lattiz)Cheese ButterMilk powder

38、Infant foodActive,medical,performance nutritionPharma applicationsChildrenAthletesElderlyPregnant women Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i

39、e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s 2019 FrieslandCampinaPrecision Fermentation Some food for thoughtI.Precision fermentation is a potential technological disruptor for the dairy industry A new opportunity to accelerate new in

40、novation avenues!II.Value-add proteins is our FCI way forward!III.Consumers seem open to the ideaIV.Challenges to overcome:technology scale up and regulatory謝謝歡迎掃碼下載課件Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s Fr i e s l a n d Ca m p i n a In g r e d i e n t s